ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax
This present research evaluated the clinical signs, histopathologicaland enzymatic changes in sheep experimentally infected with T. vivax. For this evaluation, eight male sheep, four in the control group and four infected with 105 T. vivax trypomastigotes were used. Blood samples were collected twic...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Goiás
2010-10-01
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| Series: | Ciência Animal Brasileira |
| Subjects: | |
| Online Access: | http://www.revistas.ufg.br/index.php/vet/article/view/5971/7936 |
| _version_ | 1818110403715006464 |
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| author | Katyane Sousa Almeida Fagner Luiz Costa Freitas José Hairton Tebaldi Antonio Carlos Alessi Rosangela Zacarias Machchado Adjair Antonio Nascscimento |
| author_facet | Katyane Sousa Almeida Fagner Luiz Costa Freitas José Hairton Tebaldi Antonio Carlos Alessi Rosangela Zacarias Machchado Adjair Antonio Nascscimento |
| author_sort | Katyane Sousa Almeida |
| collection | DOAJ |
| description | This present research evaluated the clinical signs, histopathologicaland enzymatic changes in sheep experimentally infected with T. vivax. For this evaluation, eight male sheep, four in the control group and four infected with 105 T. vivax trypomastigotes were used. Blood samples were collected twice before infection and on certain days after infection, evaluating the serum levels of gamma-glutamyltransferase, aspartate aminotransferase, lactate dehydrogenase, alkaline phosphatase and creatine kinase. The animals were examined daily for parasitaemia, and 120 days after infection (dpi) the animals were euthanized and necropsied with posterior liver, kidney, spleen, heart, lymph nodes, brain, lung and testicles histopathology. Wilcoxon test at 5% probability was used for the statistical analysis. The following clinical signs were found: apathy, pallor of mucous membranes, increase of superficial lymph nodes, nasal discharge and elevated rectal temperature, occasional diarrhea and nervous signs (bruxism and incoordination). Significantchanges in all biochemical parameters and histopathological parameters were found in infected animals, thus the T. vivax sample found in Paraíba, Brazil, can cause changes on enzyme levels besides clinical and important histological changes, compromising the functionality of the affected organs and resulting in metabolic dysfunction. |
| first_indexed | 2024-12-11T02:46:36Z |
| format | Article |
| id | doaj.art-ba2dc22abb0641f9b1191f359b5b46e2 |
| institution | Directory Open Access Journal |
| issn | 1518-2797 1089-6891 |
| language | English |
| last_indexed | 2024-12-11T02:46:36Z |
| publishDate | 2010-10-01 |
| publisher | Universidade Federal de Goiás |
| record_format | Article |
| series | Ciência Animal Brasileira |
| spelling | doaj.art-ba2dc22abb0641f9b1191f359b5b46e22022-12-22T01:23:26ZengUniversidade Federal de GoiásCiência Animal Brasileira1518-27971089-68912010-10-01113669676ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivaxKatyane Sousa AlmeidaFagner Luiz Costa FreitasJosé Hairton TebaldiAntonio Carlos AlessiRosangela Zacarias MachchadoAdjair Antonio NascscimentoThis present research evaluated the clinical signs, histopathologicaland enzymatic changes in sheep experimentally infected with T. vivax. For this evaluation, eight male sheep, four in the control group and four infected with 105 T. vivax trypomastigotes were used. Blood samples were collected twice before infection and on certain days after infection, evaluating the serum levels of gamma-glutamyltransferase, aspartate aminotransferase, lactate dehydrogenase, alkaline phosphatase and creatine kinase. The animals were examined daily for parasitaemia, and 120 days after infection (dpi) the animals were euthanized and necropsied with posterior liver, kidney, spleen, heart, lymph nodes, brain, lung and testicles histopathology. Wilcoxon test at 5% probability was used for the statistical analysis. The following clinical signs were found: apathy, pallor of mucous membranes, increase of superficial lymph nodes, nasal discharge and elevated rectal temperature, occasional diarrhea and nervous signs (bruxism and incoordination). Significantchanges in all biochemical parameters and histopathological parameters were found in infected animals, thus the T. vivax sample found in Paraíba, Brazil, can cause changes on enzyme levels besides clinical and important histological changes, compromising the functionality of the affected organs and resulting in metabolic dysfunction.http://www.revistas.ufg.br/index.php/vet/article/view/5971/7936Biochemicalclinical signsenzymeshistopathologysmall ruminantTrypanosomatidae |
| spellingShingle | Katyane Sousa Almeida Fagner Luiz Costa Freitas José Hairton Tebaldi Antonio Carlos Alessi Rosangela Zacarias Machchado Adjair Antonio Nascscimento ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax Ciência Animal Brasileira Biochemical clinical signs enzymes histopathology small ruminant Trypanosomatidae |
| title | ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax |
| title_full | ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax |
| title_fullStr | ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax |
| title_full_unstemmed | ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax |
| title_short | ALTERAÇÕES CLÍNICAS, HISTOPATOLÓGICAS E ENZIMÁTICAS EM OVINOS INFECTADOS EXPERIMENTALMENTE POR Trypanosoma vivax |
| title_sort | alteracoes clinicas histopatologicas e enzimaticas em ovinos infectados experimentalmente por trypanosoma vivax |
| topic | Biochemical clinical signs enzymes histopathology small ruminant Trypanosomatidae |
| url | http://www.revistas.ufg.br/index.php/vet/article/view/5971/7936 |
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