Targeted metabolomic analysis in Parkinson’s disease brain frontal cortex and putamen with relation to cognitive impairment

Abstract We performed liquid chromatography tandem mass spectrometry analysis with the targeted metabolomic kit Biocrates MxP Quant 500, in human brain cortex (Brodmann area 9) and putamen, to reveal metabolic changes characteristic of Parkinson’s disease (PD) and PD-related cognitive decline. This...

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Bibliographic Details
Main Authors: Karel Kalecký, Teodoro Bottiglieri
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00531-y

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