Bends in magnetophoretic conductors
The controlled transport of individual particles and single cells to addressable compartments is a fundamental aim in the emerging fields of lab-on-a-chip and single cell biology. Toward this goal, magnetophoretic circuits, by providing precise control over individual particles in a highly parallel...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2019-12-01
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| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/1.5114883 |
| _version_ | 1818846957258407936 |
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| author | Roozbeh Abedini-Nassab Reza Shourabi |
| author_facet | Roozbeh Abedini-Nassab Reza Shourabi |
| author_sort | Roozbeh Abedini-Nassab |
| collection | DOAJ |
| description | The controlled transport of individual particles and single cells to addressable compartments is a fundamental aim in the emerging fields of lab-on-a-chip and single cell biology. Toward this goal, magnetophoretic circuits, by providing precise control over individual particles in a highly parallel manner, have shown to be a unique competitor for the rivals in the field. In these matter transport platforms, magnetic thin films provide a predefined trajectory for the magnetic microbeads and magnetically labeled cells toward the desired spots. These magnetic paths, called magnetophoretic conductors, are usually placed in horizontal or vertical directions in a circuit; however, we have made no prior attempts to optimize the design of the junctions and the bends in the conductors. Here, we provide an optimization analysis of the bends based on variation in the particle’s size. Considering the achieved results, we designed multiple bends with high performance in transporting magnetized particles and cells. Applying these designs to the magnetophoretic circuits results in a robust, multiplexed platform capable of manipulating microbeads and single cells with important applications in biology, immunology, and drug screening. |
| first_indexed | 2024-12-19T05:53:48Z |
| format | Article |
| id | doaj.art-ba353148f8294d19b138129656d91e08 |
| institution | Directory Open Access Journal |
| issn | 2158-3226 |
| language | English |
| last_indexed | 2024-12-19T05:53:48Z |
| publishDate | 2019-12-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | AIP Advances |
| spelling | doaj.art-ba353148f8294d19b138129656d91e082022-12-21T20:33:32ZengAIP Publishing LLCAIP Advances2158-32262019-12-01912125121125121-810.1063/1.5114883Bends in magnetophoretic conductorsRoozbeh Abedini-Nassab0Reza Shourabi1Department of Biomedical Engineering, University of Neyshabur, Neyshabur 9319774400, IranDepartment of Electrical Engineering, University of Neyshabur, Neyshabur 9319774400, IranThe controlled transport of individual particles and single cells to addressable compartments is a fundamental aim in the emerging fields of lab-on-a-chip and single cell biology. Toward this goal, magnetophoretic circuits, by providing precise control over individual particles in a highly parallel manner, have shown to be a unique competitor for the rivals in the field. In these matter transport platforms, magnetic thin films provide a predefined trajectory for the magnetic microbeads and magnetically labeled cells toward the desired spots. These magnetic paths, called magnetophoretic conductors, are usually placed in horizontal or vertical directions in a circuit; however, we have made no prior attempts to optimize the design of the junctions and the bends in the conductors. Here, we provide an optimization analysis of the bends based on variation in the particle’s size. Considering the achieved results, we designed multiple bends with high performance in transporting magnetized particles and cells. Applying these designs to the magnetophoretic circuits results in a robust, multiplexed platform capable of manipulating microbeads and single cells with important applications in biology, immunology, and drug screening.http://dx.doi.org/10.1063/1.5114883 |
| spellingShingle | Roozbeh Abedini-Nassab Reza Shourabi Bends in magnetophoretic conductors AIP Advances |
| title | Bends in magnetophoretic conductors |
| title_full | Bends in magnetophoretic conductors |
| title_fullStr | Bends in magnetophoretic conductors |
| title_full_unstemmed | Bends in magnetophoretic conductors |
| title_short | Bends in magnetophoretic conductors |
| title_sort | bends in magnetophoretic conductors |
| url | http://dx.doi.org/10.1063/1.5114883 |
| work_keys_str_mv | AT roozbehabedininassab bendsinmagnetophoreticconductors AT rezashourabi bendsinmagnetophoreticconductors |