Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit
Background and Objectives: This study aimed to investigate epidemiology of Staphylococcus epidermidis (S. epidermidis) and Acinetobacter baumannii (A. baumannii) infections in neonatal intensive care unit (NICU) in a period of 8 years. Materials and Methods: This retrospective cohort study was cond...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-06-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/4123 |
| _version_ | 1797800728797904896 |
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| author | Fatemeh Nayeri Hosein Dalili Mamak Shariat Nahid Farrokhzad Kosar Abouhamzeh Leyla Sahebi |
| author_facet | Fatemeh Nayeri Hosein Dalili Mamak Shariat Nahid Farrokhzad Kosar Abouhamzeh Leyla Sahebi |
| author_sort | Fatemeh Nayeri |
| collection | DOAJ |
| description |
Background and Objectives: This study aimed to investigate epidemiology of Staphylococcus epidermidis (S. epidermidis) and Acinetobacter baumannii (A. baumannii) infections in neonatal intensive care unit (NICU) in a period of 8 years.
Materials and Methods: This retrospective cohort study was conducted on 46 cases of nosocomial infection by S. epidermidis, and 44 neonates with A. baumannii in NICU of Valiasr hospital, Iran.
Results: The trend of A. baumannii and S. epidermidis infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with S. epidermidis and A. baumannii infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the A. baumannii infection in month too. Amikacin prescription had adjusted correlation on increasing of A. baumannii and S. epidermidis infection in month.
Conclusion: It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections.
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| first_indexed | 2024-03-13T04:39:38Z |
| format | Article |
| id | doaj.art-ba36ed01c43943279b08aa98e33a6711 |
| institution | Directory Open Access Journal |
| issn | 2008-3289 2008-4447 |
| language | English |
| last_indexed | 2024-03-13T04:39:38Z |
| publishDate | 2023-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj.art-ba36ed01c43943279b08aa98e33a67112023-06-19T06:29:58ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472023-06-0115310.18502/ijm.v15i3.12895Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unitFatemeh Nayeri0Hosein Dalili1Mamak Shariat2Nahid Farrokhzad3Kosar Abouhamzeh4Leyla Sahebi5Maternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, IranBreastfeeding Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, IranMaternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, IranMaternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, IranStudents' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, IranMaternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran Background and Objectives: This study aimed to investigate epidemiology of Staphylococcus epidermidis (S. epidermidis) and Acinetobacter baumannii (A. baumannii) infections in neonatal intensive care unit (NICU) in a period of 8 years. Materials and Methods: This retrospective cohort study was conducted on 46 cases of nosocomial infection by S. epidermidis, and 44 neonates with A. baumannii in NICU of Valiasr hospital, Iran. Results: The trend of A. baumannii and S. epidermidis infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with S. epidermidis and A. baumannii infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the A. baumannii infection in month too. Amikacin prescription had adjusted correlation on increasing of A. baumannii and S. epidermidis infection in month. Conclusion: It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections. https://ijm.tums.ac.ir/index.php/ijm/article/view/4123Acinetobacter baumannii;Staphylococcus epidermidis;Outbreak;Neonatal intensive care units;Nosocomial infections |
| spellingShingle | Fatemeh Nayeri Hosein Dalili Mamak Shariat Nahid Farrokhzad Kosar Abouhamzeh Leyla Sahebi Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit Iranian Journal of Microbiology Acinetobacter baumannii; Staphylococcus epidermidis; Outbreak; Neonatal intensive care units; Nosocomial infections |
| title | Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit |
| title_full | Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit |
| title_fullStr | Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit |
| title_full_unstemmed | Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit |
| title_short | Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a neonatal intensive care unit |
| title_sort | epidemiology of nosocomial staphylococcus epidermidis and acinetobacter baumannii infections in a neonatal intensive care unit |
| topic | Acinetobacter baumannii; Staphylococcus epidermidis; Outbreak; Neonatal intensive care units; Nosocomial infections |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/4123 |
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