Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database
Numerous studies have shown the importance of breed-related differences between hematological and biochemical results in veterinary medicine. The aim of this study is to determine hematologic and biochemical Reference Intervals (RIs) for 5 hunting dog breeds from a blood donor database, adopting an...
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MDPI AG
2020-07-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/10/7/1212 |
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| author | Arianna Miglio Alessandra Gavazza Donatella Siepi Francesco Bagaglia Ambra Misia Maria Teresa Antognoni |
| author_facet | Arianna Miglio Alessandra Gavazza Donatella Siepi Francesco Bagaglia Ambra Misia Maria Teresa Antognoni |
| author_sort | Arianna Miglio |
| collection | DOAJ |
| description | Numerous studies have shown the importance of breed-related differences between hematological and biochemical results in veterinary medicine. The aim of this study is to determine hematologic and biochemical Reference Intervals (RIs) for 5 hunting dog breeds from a blood donor database, adopting an indirect sampling method, and to compare them with laboratory established and published RIs to identify possible breed and attitude-related differences. The study analyzed the blood parameters of 445 adults (222 females and 223 male, with age ranging from 2 to 8 years, mean age 5.3 years), client-owned, clinically healthy blood donor dogs of 5 breeds: 156 Ariégeois, 52 Bleu de Gascogne, 64 Bracco italiano, 123 Segugio italiano, and 50 Briquet Griffon Vandeen. Statistical analysis was performed as recommended by the American Society of Veterinary Clinical Pathology (ASVCP) guidelines. RIs for red blood cells (RBC), hematocrit (HCT), hemoglobin (HB), main corpuscular volume (MCV), main corpuscular hemoglobin (MCH), main corpuscular hemoglobin concentration (MCHC), red distribution widht (RDW), white blood cells (WBC), and differential leukocytes count, PLT, Albumin, Total Protein, Urea, Creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) for each of the 5 breeds were performed, and significant differences with the established RIs were detected. We found significant differences in 12 hematologic and serum biochemical analytes for which a breed-specific variation appears to be the most plausible explanation. New RIs for HCT, MCH, MCHC, RDW, PLT, Monocytes, Eosinophils, Albumin, Urea, Creatinine, AST, and ALT are provided for at least 1 breed. Breed-specific RIs for adult hunting dogs will help avoid misinterpretation of laboratory results in these breeds. |
| first_indexed | 2024-03-10T18:26:59Z |
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| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T18:26:59Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-ba37fd89881443c4801551f04ab29df62023-11-20T06:58:06ZengMDPI AGAnimals2076-26152020-07-01107121210.3390/ani10071212Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor DatabaseArianna Miglio0Alessandra Gavazza1Donatella Siepi2Francesco Bagaglia3Ambra Misia4Maria Teresa Antognoni5Department of Veterinary Medicine, Blood Bank and Transfusion Unit EMOVET-UNIPG, University of Perugia, 06126 Perugia, ItalySchool of Bioscences and Veterinary Medicine, University of Camerino, 62024 Camerino, ItalyDepartment of Medicine, University of Perugia, 06124 Perugia, ItalyDepartment of Medicine, University of Perugia, 06124 Perugia, ItalyDepartment of Veterinary Medicine, Blood Bank and Transfusion Unit EMOVET-UNIPG, University of Perugia, 06126 Perugia, ItalyDepartment of Veterinary Medicine, Blood Bank and Transfusion Unit EMOVET-UNIPG, University of Perugia, 06126 Perugia, ItalyNumerous studies have shown the importance of breed-related differences between hematological and biochemical results in veterinary medicine. The aim of this study is to determine hematologic and biochemical Reference Intervals (RIs) for 5 hunting dog breeds from a blood donor database, adopting an indirect sampling method, and to compare them with laboratory established and published RIs to identify possible breed and attitude-related differences. The study analyzed the blood parameters of 445 adults (222 females and 223 male, with age ranging from 2 to 8 years, mean age 5.3 years), client-owned, clinically healthy blood donor dogs of 5 breeds: 156 Ariégeois, 52 Bleu de Gascogne, 64 Bracco italiano, 123 Segugio italiano, and 50 Briquet Griffon Vandeen. Statistical analysis was performed as recommended by the American Society of Veterinary Clinical Pathology (ASVCP) guidelines. RIs for red blood cells (RBC), hematocrit (HCT), hemoglobin (HB), main corpuscular volume (MCV), main corpuscular hemoglobin (MCH), main corpuscular hemoglobin concentration (MCHC), red distribution widht (RDW), white blood cells (WBC), and differential leukocytes count, PLT, Albumin, Total Protein, Urea, Creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) for each of the 5 breeds were performed, and significant differences with the established RIs were detected. We found significant differences in 12 hematologic and serum biochemical analytes for which a breed-specific variation appears to be the most plausible explanation. New RIs for HCT, MCH, MCHC, RDW, PLT, Monocytes, Eosinophils, Albumin, Urea, Creatinine, AST, and ALT are provided for at least 1 breed. Breed-specific RIs for adult hunting dogs will help avoid misinterpretation of laboratory results in these breeds.https://www.mdpi.com/2076-2615/10/7/1212blood donorsbreedhunting dogshematologybiochemistryreference intervals |
| spellingShingle | Arianna Miglio Alessandra Gavazza Donatella Siepi Francesco Bagaglia Ambra Misia Maria Teresa Antognoni Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database Animals blood donors breed hunting dogs hematology biochemistry reference intervals |
| title | Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database |
| title_full | Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database |
| title_fullStr | Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database |
| title_full_unstemmed | Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database |
| title_short | Hematological and Biochemical Reference Intervals for 5 Adult Hunting Dog Breeds Using a Blood Donor Database |
| title_sort | hematological and biochemical reference intervals for 5 adult hunting dog breeds using a blood donor database |
| topic | blood donors breed hunting dogs hematology biochemistry reference intervals |
| url | https://www.mdpi.com/2076-2615/10/7/1212 |
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