A Case of Resistant Megaloblastic Anemia Responding to Thiamine
Thiamine responsive megaloblastic anemia (TRMA), also known as Roger syndrome is an autosomal recessive disorder resulting from the deficiency of thiamine (Vitamin B1) transporter protein. This is the report of a 3- year follow up of a female child who presented in 2000 at the age of 11 with severe...
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| Format: | Article |
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Shahid Sadoughi University of Medical Sciences
2006-01-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
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| Online Access: | http://jssu.ssu.ac.ir/browse.php?a_id=567&slc_lang=en&sid=1&ftxt=1 |
| _version_ | 1811284617782624256 |
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| author | A Bahrami- Ahmadi F Binesh MR Mortazavizadeh |
| author_facet | A Bahrami- Ahmadi F Binesh MR Mortazavizadeh |
| author_sort | A Bahrami- Ahmadi |
| collection | DOAJ |
| description | Thiamine responsive megaloblastic anemia (TRMA), also known as Roger syndrome is an autosomal recessive disorder resulting from the deficiency of thiamine (Vitamin B1) transporter protein. This is the report of a 3- year follow up of a female child who presented in 2000 at the age of 11 with severe anemia, congenital deafness and diabetes mellitus. In our follow-up period we prescribed 100-mg thiamine tablet daily and after that there was a rise in her hemoglobin level to normal. Her hyperglycemia was controlled during the early phase of treatment. It recurred several months after start of treatment, but needed lower doses of insulin for control. Hearing loss did not respond to thiamine. Presently, the patient is apparently in good condition with normal hemoglobin level. |
| first_indexed | 2024-04-13T02:32:17Z |
| format | Article |
| id | doaj.art-ba38a70d8e3047f1b76ab88d0d1a54bd |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-04-13T02:32:17Z |
| publishDate | 2006-01-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-ba38a70d8e3047f1b76ab88d0d1a54bd2022-12-22T03:06:31ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332006-01-011357579A Case of Resistant Megaloblastic Anemia Responding to ThiamineA Bahrami- AhmadiF BineshMR MortazavizadehThiamine responsive megaloblastic anemia (TRMA), also known as Roger syndrome is an autosomal recessive disorder resulting from the deficiency of thiamine (Vitamin B1) transporter protein. This is the report of a 3- year follow up of a female child who presented in 2000 at the age of 11 with severe anemia, congenital deafness and diabetes mellitus. In our follow-up period we prescribed 100-mg thiamine tablet daily and after that there was a rise in her hemoglobin level to normal. Her hyperglycemia was controlled during the early phase of treatment. It recurred several months after start of treatment, but needed lower doses of insulin for control. Hearing loss did not respond to thiamine. Presently, the patient is apparently in good condition with normal hemoglobin level.http://jssu.ssu.ac.ir/browse.php?a_id=567&slc_lang=en&sid=1&ftxt=1ThiamineAnemiaMegaloblastic |
| spellingShingle | A Bahrami- Ahmadi F Binesh MR Mortazavizadeh A Case of Resistant Megaloblastic Anemia Responding to Thiamine Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd Thiamine Anemia Megaloblastic |
| title | A Case of Resistant Megaloblastic Anemia Responding to Thiamine |
| title_full | A Case of Resistant Megaloblastic Anemia Responding to Thiamine |
| title_fullStr | A Case of Resistant Megaloblastic Anemia Responding to Thiamine |
| title_full_unstemmed | A Case of Resistant Megaloblastic Anemia Responding to Thiamine |
| title_short | A Case of Resistant Megaloblastic Anemia Responding to Thiamine |
| title_sort | case of resistant megaloblastic anemia responding to thiamine |
| topic | Thiamine Anemia Megaloblastic |
| url | http://jssu.ssu.ac.ir/browse.php?a_id=567&slc_lang=en&sid=1&ftxt=1 |
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