Long Noncoding RNA EGFR-AS1 Promotes Cell Proliferation by Increasing EGFR mRNA Stability in Gastric Cancer

Long Noncoding RNA EGFR-AS1 Promotes Cell Proliferation by Increasing EGFR mRNA Stability in Gastric Cancer

Background/Aims: LncRNA EGFR-AS1 is an antisense transcript of EGFR, which plays a key role in gastric cancer progression. This study was aimed to explore the effects of lncRNA EGFR-AS1 on GC and the underling mechanisms. Methods: The silencing of EGFR-AS1 expression was performed by using EGFR-AS1...

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Bibliographic Details
Main Authors: Jiaojiao Hu, Yingying Qian, Lipan Peng, Ling Ma, Tianzhu Qiu, Yiqian Liu, Xiao Li, Xiaofeng  Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
lncRNAs
Gastric cancer
EGFR-AS1
EGFR
MRNA stability
PI3K
Online Access:https://www.karger.com/Article/FullText/492883

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