T-Cadherin Expression in Melanoma Cells Stimulates Stromal Cell Recruitment and Invasion by Regulating the Expression of Chemokines, Integrins and Adhesion Molecules

T-Cadherin Expression in Melanoma Cells Stimulates Stromal Cell Recruitment and Invasion by Regulating the Expression of Chemokines, Integrins and Adhesion Molecules

T-cadherin is a glycosyl-phosphatidylinositol (GPI) anchored member of the cadherin superfamily involved in the guidance of migrating cells. We have previously shown that in vivo T-cadherin overexpression leads to increased melanoma primary tumor growth due to the recruitment of mesenchymal stromal...

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Bibliographic Details
Main Authors: Kseniya A. Rubina, Ekaterina I. Surkova, Ekaterina V. Semina, Veronika Y. Sysoeva, Natalia I. Kalinina, Alexei A. Poliakov, Helena M. Treshalina, Vsevolod A. Tkachuk
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Cancers
Subjects:
T-cadherin
melanoma
migration
invasion
Online Access:http://www.mdpi.com/2072-6694/7/3/0840

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