Role of endothelial hyaluronan in peritoneal membrane transport and disease conditions during peritoneal dialysis

Role of endothelial hyaluronan in peritoneal membrane transport and disease conditions during peritoneal dialysis

Abstract Peritoneal membrane dysfunction in peritoneal dialysis (PD) is primarily attributed to angiogenesis; however, the integrity of vascular endothelial cells can affect peritoneal permeability. Hyaluronan, a component of the endothelial glycocalyx, is reportedly involved in preventing proteinur...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Keisuke Kamiya, Naoyuki Hatayama, Mitsuhiro Tawada, Akimasa Asai, Mai Yamauchi, Hiroshi Kinashi, Shunnosuke Kunoki, Makoto Yamaguchi, Masashi Mizuno, Yasuhiro Suzuki, Masataka Banshodani, Takuji Ishimoto, Munekazu Naito, Hideki Kawanishi, Yasuhiko Ito
Format: Artikel
Sprache:English
Veröffentlicht: Nature Portfolio 2024-03-01
Schriftenreihe:Scientific Reports
Schlagworte:
Glycocalyx
Hyaluronan
Peritoneal transport
Macromolecules
Protein leakage
EPS
Online Zugang:https://doi.org/10.1038/s41598-024-58148-x

Online

https://doi.org/10.1038/s41598-024-58148-x

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