Role of endothelial hyaluronan in peritoneal membrane transport and disease conditions during peritoneal dialysis

Role of endothelial hyaluronan in peritoneal membrane transport and disease conditions during peritoneal dialysis

Abstract Peritoneal membrane dysfunction in peritoneal dialysis (PD) is primarily attributed to angiogenesis; however, the integrity of vascular endothelial cells can affect peritoneal permeability. Hyaluronan, a component of the endothelial glycocalyx, is reportedly involved in preventing proteinur...

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Bibliographic Details
Main Authors: Keisuke Kamiya, Naoyuki Hatayama, Mitsuhiro Tawada, Akimasa Asai, Mai Yamauchi, Hiroshi Kinashi, Shunnosuke Kunoki, Makoto Yamaguchi, Masashi Mizuno, Yasuhiro Suzuki, Masataka Banshodani, Takuji Ishimoto, Munekazu Naito, Hideki Kawanishi, Yasuhiko Ito
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Glycocalyx
Hyaluronan
Peritoneal transport
Macromolecules
Protein leakage
EPS
Online Access:https://doi.org/10.1038/s41598-024-58148-x

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