Synergistic anticancer activity of cisplatin combined with tannic acid enhances apoptosis in lung cancer through the PERK-ATF4 pathway

Synergistic anticancer activity of cisplatin combined with tannic acid enhances apoptosis in lung cancer through the PERK-ATF4 pathway

Abstract Background Cisplatin (CDDP) is a common anticancer drug whose side effects limit its clinical applications. Tannins (TA) are plant-derived polyphenols that inhibit tumor growth in different types of cancer. Here, we evaluated the anticancer effect of TA combined with CDDP on lung cancer cel...

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Bibliographic Details
Main Authors: Xiang Zheng, Lei Yang, Wei Zhai, Nana Geng, Zhimin Zhang, Xueying Li, Mingsong Wu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:European Journal of Medical Research
Subjects:
Lung cancer
Endoplasmic reticulum stress
Tannins
Cisplatin
Combination drugs
Online Access:https://doi.org/10.1186/s40001-023-01420-z

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