Study of Melatonin as Preventive Agent of Gastrointestinal Damage Induced by Sodium Diclofenac

Study of Melatonin as Preventive Agent of Gastrointestinal Damage Induced by Sodium Diclofenac

Safety profile of nonsteroidal anti-inflammatory drugs (NSAIDs) has been widely studied and both therapeutic and side effects at the gastric and cardiovascular level have been generally associated with the inhibitory effect of isoform 1 (COX-1) and 2 (COX-2) cyclooxygenase enzymes. Now there are evi...

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Bibliographic Details
Main Authors: Aroha B. Sánchez, Beatriz Clares, María J. Rodríguez-Lagunas, María J. Fábrega, Ana C. Calpena
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
melatonin
nsaids
gastric injuries
antioxidant
Online Access:https://www.mdpi.com/2073-4409/9/1/180

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