Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes
<b>Aim:</b> To increase the frequency of pregnancy and delivery rate in in vitro fertilization cycles using native and vitrified donor oocytes.<br> <b>Methods:</b> Analyzing the results of in vitro fertilization in 62 patients who had oocyte d...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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National Scientific Medical Center
2018-12-01
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| Series: | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| Subjects: | |
| Online Access: | https://www.clinmedkaz.org/download/analysis-of-effectiveness-of-in-vitro-fertilization-using-vitrificated-and-native-donor-oocytes-9035.pdf |
| _version_ | 1818500788740161536 |
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| author | Mykola Gryshchenko Andrey Lutskiy |
| author_facet | Mykola Gryshchenko Andrey Lutskiy |
| author_sort | Mykola Gryshchenko |
| collection | DOAJ |
| description | <b>Aim:</b> To increase the frequency of pregnancy and delivery rate in in vitro fertilization cycles using native and vitrified donor oocytes.<br>
<b>Methods:</b> Analyzing the results of in vitro fertilization in 62 patients who had oocyte donation programs. Patients were divided into 2 groups: the 1<sup>st</sup> group included 27 women who had used vitrified donor oocytes, and the 2<sup>nd</sup> group - 35 patients to whom the native oocytes of the donor were used in the in vitro fertilization cycle. The obtained oocytes were vitrified according to the standard technique using the Cryotech Vitrification kit. To prepare the endometrium for the transfer of embryos, a preparatory hormonal therapy regimen was used and the embryos were transferred in a modified menstrual cycle.<br>
<b>Results:</b> Studies have shown that the application of the vitrification method in assisted reproductive technology programs allows to achieve clinical results that are not inferior and even significantly exceed the effectiveness of treatment in cycles with native donor oocytes in such parameters as clinical pregnancies, implantation rate and labor.<br>
<b>Conclusion:</b> Vitrification is an effective method of cryopreservation of oocytes, which allows to preserve the functional properties of the eggs and, after their fertilization, to obtain embryos with high implantation potential. |
| first_indexed | 2024-12-10T20:47:31Z |
| format | Article |
| id | doaj.art-ba4b90ece9c24fe2a5fe4c9f15abe199 |
| institution | Directory Open Access Journal |
| issn | 1812-2892 2313-1519 |
| language | English |
| last_indexed | 2024-12-10T20:47:31Z |
| publishDate | 2018-12-01 |
| publisher | National Scientific Medical Center |
| record_format | Article |
| series | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| spelling | doaj.art-ba4b90ece9c24fe2a5fe4c9f15abe1992022-12-22T01:34:12ZengNational Scientific Medical CenterĶazaķstannyṇ Klinikalyķ Medicinasy1812-28922313-15192018-12-01450303310.23950/1812-2892-JCMK-00599Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytesMykola Gryshchenko0Andrey Lutskiy1Сlinic of Reproductive Medicine, Kharkov, UkraineDepartment of Obstetrics and Gynecology, Kharkov National Medical University, Kharkov, Ukraine<b>Aim:</b> To increase the frequency of pregnancy and delivery rate in in vitro fertilization cycles using native and vitrified donor oocytes.<br> <b>Methods:</b> Analyzing the results of in vitro fertilization in 62 patients who had oocyte donation programs. Patients were divided into 2 groups: the 1<sup>st</sup> group included 27 women who had used vitrified donor oocytes, and the 2<sup>nd</sup> group - 35 patients to whom the native oocytes of the donor were used in the in vitro fertilization cycle. The obtained oocytes were vitrified according to the standard technique using the Cryotech Vitrification kit. To prepare the endometrium for the transfer of embryos, a preparatory hormonal therapy regimen was used and the embryos were transferred in a modified menstrual cycle.<br> <b>Results:</b> Studies have shown that the application of the vitrification method in assisted reproductive technology programs allows to achieve clinical results that are not inferior and even significantly exceed the effectiveness of treatment in cycles with native donor oocytes in such parameters as clinical pregnancies, implantation rate and labor.<br> <b>Conclusion:</b> Vitrification is an effective method of cryopreservation of oocytes, which allows to preserve the functional properties of the eggs and, after their fertilization, to obtain embryos with high implantation potential.https://www.clinmedkaz.org/download/analysis-of-effectiveness-of-in-vitro-fertilization-using-vitrificated-and-native-donor-oocytes-9035.pdfin vitro fertilizationnative and vitrificated donor oocytesoocyte survivability |
| spellingShingle | Mykola Gryshchenko Andrey Lutskiy Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes Ķazaķstannyṇ Klinikalyķ Medicinasy in vitro fertilization native and vitrificated donor oocytes oocyte survivability |
| title | Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes |
| title_full | Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes |
| title_fullStr | Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes |
| title_full_unstemmed | Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes |
| title_short | Analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes |
| title_sort | analysis of effectiveness of in vitro fertilization using vitrificated and native donor oocytes |
| topic | in vitro fertilization native and vitrificated donor oocytes oocyte survivability |
| url | https://www.clinmedkaz.org/download/analysis-of-effectiveness-of-in-vitro-fertilization-using-vitrificated-and-native-donor-oocytes-9035.pdf |
| work_keys_str_mv | AT mykolagryshchenko analysisofeffectivenessofinvitrofertilizationusingvitrificatedandnativedonoroocytes AT andreylutskiy analysisofeffectivenessofinvitrofertilizationusingvitrificatedandnativedonoroocytes |