Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium

Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium

Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are not fully understood. Herein, analyses with the attaching/effacing pathogen Citrobacter rodentium model of colitis...

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Bibliographic Details
Main Authors: Ravi Holani, Chathurika Rathnayaka, Graham A.D. Blyth, Anshu Babbar, Priyoshi Lahiri, Daniel Young, Antoine Dufour, Morley D. Hollenberg, Derek M. McKay, Eduardo R. Cobo
Format: Article
Language:English
Published: Karger Publishers 2022-09-01
Series:Journal of Innate Immunity
Subjects:
colonic epithelium
apoptosis
tollip
cathelicidin
mirna
Online Access:https://www.karger.com/Article/FullText/526121

Internet

https://www.karger.com/Article/FullText/526121

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