Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting
Similar symptoms between viral and bacterial diseases often make diagnosis difficult. This study assessed the clinical performance of the newly cleared whole-blood Bacterial versus Viral Score assay in our pediatric cohort to the previously validated serum assay and emergency department physician di...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
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| Series: | Practical Laboratory Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352551724000337 |
| _version_ | 1827316941172244480 |
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| author | Ridwan B. Ibrahim Herda Ona Anil K. Chokkalla Estella Tam Sridevi Devaraj |
| author_facet | Ridwan B. Ibrahim Herda Ona Anil K. Chokkalla Estella Tam Sridevi Devaraj |
| author_sort | Ridwan B. Ibrahim |
| collection | DOAJ |
| description | Similar symptoms between viral and bacterial diseases often make diagnosis difficult. This study assessed the clinical performance of the newly cleared whole-blood Bacterial versus Viral Score assay in our pediatric cohort to the previously validated serum assay and emergency department physician diagnosis. This assay shows excellent agreement (R = 0.997) with the serum assay and has great diagnostic accuracy when compared to physician diagnosis. |
| first_indexed | 2024-04-24T23:24:09Z |
| format | Article |
| id | doaj.art-ba4e4454c5184285bd15269c9807dd19 |
| institution | Directory Open Access Journal |
| issn | 2352-5517 |
| language | English |
| last_indexed | 2024-04-24T23:24:09Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Practical Laboratory Medicine |
| spelling | doaj.art-ba4e4454c5184285bd15269c9807dd192024-03-16T05:08:38ZengElsevierPractical Laboratory Medicine2352-55172024-03-0139e00387Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital settingRidwan B. Ibrahim0Herda Ona1Anil K. Chokkalla2Estella Tam3Sridevi Devaraj4Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Department of Pathology, Texas Children's Hospital, Houston, TX, USADepartment of Pathology, Texas Children's Hospital, Houston, TX, USADepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USADepartment of Pathology, Texas Children's Hospital, Houston, TX, USADepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA; Corresponding author. Department of Pathology & Immunology, Baylor College of Medicine, Texas Children's Hospital, 6621 Fannin Street, West Tower, Pathology BB110.06, Houston, TX, 77030, USA.Similar symptoms between viral and bacterial diseases often make diagnosis difficult. This study assessed the clinical performance of the newly cleared whole-blood Bacterial versus Viral Score assay in our pediatric cohort to the previously validated serum assay and emergency department physician diagnosis. This assay shows excellent agreement (R = 0.997) with the serum assay and has great diagnostic accuracy when compared to physician diagnosis.http://www.sciencedirect.com/science/article/pii/S2352551724000337InfectionViremiaBacteraemiaAntibiotics |
| spellingShingle | Ridwan B. Ibrahim Herda Ona Anil K. Chokkalla Estella Tam Sridevi Devaraj Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting Practical Laboratory Medicine Infection Viremia Bacteraemia Antibiotics |
| title | Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting |
| title_full | Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting |
| title_fullStr | Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting |
| title_full_unstemmed | Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting |
| title_short | Validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting |
| title_sort | validation of a whole blood machine learning strategy for distinguishing between bacterial and viral infection in a pediatric hospital setting |
| topic | Infection Viremia Bacteraemia Antibiotics |
| url | http://www.sciencedirect.com/science/article/pii/S2352551724000337 |
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