Pyrene-modified PNAs: Stacking interactions and selective excimer emission in PNA2DNA triplexes

Pyrene-modified PNAs: Stacking interactions and selective excimer emission in PNA2DNA triplexes

Pyrene derivatives can be incorporated into nucleic acid analogs in order to obtain switchable probes or supramolecular architectures. In this paper, peptide nucleic acids (PNAs) containing 1 to 3 1-pyreneacetic acid units (PNA1–6) with a sequence with prevalence of pyrimidine bases, complementary t...

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Bibliographic Details
Main Authors: Alex Manicardi, Lucia Guidi, Alice Ghidini, Roberto Corradini
Format: Article
Language:English
Published: Beilstein-Institut 2014-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
modified nucleobase
nucleic acids
PNA
pyrene excimer
SNP recognition
triplex stabilization
Online Access:https://doi.org/10.3762/bjoc.10.154

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