Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning.
We have used a previously unavailable model of pancreatic development, derived in vitro from human embryonic stem cells, to capture a time-course of gene, miRNA and histone modification levels in pancreatic endocrine cells. We investigated whether it is possible to better understand, and hence contr...
Main Authors: | Alex Gutteridge, J Michael Rukstalis, Daniel Ziemek, Mark Tié, Lin Ji, Rebeca Ramos-Zayas, Nancy A Nardone, Lisa D Norquay, Martin B Brenner, Kim Tang, John D McNeish, Rebecca K Rowntree |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3572136?pdf=render |
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