Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway
Cardiac hypertrophy is a major risk factor for heart failure and leads to cardiovascular morbidity and mortality. Doxorubicin (DOX) is regarded as one of the most potent anthracycline antibiotic agents; however, its clinical usage has some limitations because it has serious cardiotoxic side effects...
Main Authors: | Jung Joo Yoon, Chan Ok Son, Hye Yoom Kim, Byung Hyuk Han, Yun Jung Lee, Ho Sub Lee, Dae Gill Kang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/1/53 |
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