The Effect of Tranexamic Acid Administration on Early Endothelial Damage Following Posterior Lumbar Fusion Surgery

The Effect of Tranexamic Acid Administration on Early Endothelial Damage Following Posterior Lumbar Fusion Surgery

Tranexamic acid (TXA) protects against endothelial glycocalyx injury in vitro. We aimed to evaluate whether TXA could protect against endothelial glycocalyx degradation in patients undergoing posterior lumbar fusion surgery. Patients aged 30–80 years were enrolled. The TXA group was administered a l...

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Bibliographic Details
Main Authors: Hye Jin Kim, Bora Lee, Byung Ho Lee, So Yeon Kim, Byongnam Jun, Yong Seon Choi
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Clinical Medicine
Subjects:
tranexamic acid
endothelial glycocalyx
spinal surgery
syndecan-1
heparan sulfate
Online Access:https://www.mdpi.com/2077-0383/10/7/1415

Internet

https://www.mdpi.com/2077-0383/10/7/1415

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