Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in mice

Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in mice

Summary Extracellular vesicles (EVs) released by cells in the bone marrow (BM) are important for regulating proliferation, differentiation, and other processes in hematopoietic stem cells (HSC). TGF-β signaling is now well known to be involved in HSC’s quiescence and maintenance, but the TGF-β pathw...

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Bibliographic Details
Main Authors:	Flavie Gautheron, Aleksandra Georgievski, Carmen Garrido, Ronan Quéré
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-04-01
Series:	Cell Death Discovery
Online Access:	https://doi.org/10.1038/s41420-023-01414-0

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