Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in mice
Summary Extracellular vesicles (EVs) released by cells in the bone marrow (BM) are important for regulating proliferation, differentiation, and other processes in hematopoietic stem cells (HSC). TGF-β signaling is now well known to be involved in HSC’s quiescence and maintenance, but the TGF-β pathw...
Main Authors: | Flavie Gautheron, Aleksandra Georgievski, Carmen Garrido, Ronan Quéré |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
|
Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01414-0 |
Similar Items
-
Melatonin and TGF-β-Mediated Release of Extracellular Vesicles
by: Klaudia Piekarska, et al.
Published: (2023-04-01) -
Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway
by: Lin Zhang, et al.
Published: (2021-11-01) -
Bone Marrow Mesenchymal Stem Cells Release miR-378a-5p-Carried Extracellular Vesicles to Alleviate Rheumatoid Arthritis
by: Yaqin Zhang, et al.
Published: (2023-11-01) -
Effect of progesterone on Smad signaling and TGF-β/Smad-regulated genes in lung epithelial cells.
by: Steffen Kunzmann, et al.
Published: (2018-01-01) -
α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis
by: Pan Wang, et al.
Published: (2023-08-01)