The Association Between Documentation of Koplik Spots and Laboratory Diagnosis of Measles and Other Rash Diseases in a National Measles Surveillance Program in Japan

The Association Between Documentation of Koplik Spots and Laboratory Diagnosis of Measles and Other Rash Diseases in a National Measles Surveillance Program in Japan

Koplik spots are considered a disease-specific sign for measles, although comprehensive virological studies have not been conducted to date. In Japan, a national survey of 3023 measles and measles-suspected cases was conducted between 2009 and 2014 using polymerase chain reaction (PCR) or reverse tr...

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Bibliographic Details
Main Authors: Hirokazu Kimura, Komei Shirabe, Makoto Takeda, Miho Kobayashi, Hiroyuki Tsukagoshi, Kaori Okayama, Akihide Ryo, Koo Nagasawa, Nobuhiko Okabe, Hiroko Minagawa, Kunihisa Kozawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
measles
Koplik spots
RT-PCR
rash and fever
viral infection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00269/full

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