Pentamethylquercetin Regulates Lipid Metabolism by Modulating Skeletal Muscle-Adipose Tissue Crosstalk in Obese Mice

Pentamethylquercetin Regulates Lipid Metabolism by Modulating Skeletal Muscle-Adipose Tissue Crosstalk in Obese Mice

Irisin is an exercise-induced hormone that regulates lipid metabolism. The present study investigates whether the anti-obesity effect of the natural flavonoid pentamethylquercetin (PMQ) is related to irisin secretion from skeletal muscle in whole animals and cultured cells. Obese mice induced by mon...

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Bibliographic Details
Main Authors: Jianzhao Wu, Jingxia Du, Zhi Li, Wei He, Min Wang, Manwen Jin, Lei Yang, Hui Liu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
pentamethylquercetin
skeletal muscle
irisin
browning of white adipose tissue
AMP-activated protein kinase
peroxisome proliferator-activated receptor-γ coactivator-1α
Online Access:https://www.mdpi.com/1999-4923/14/6/1159

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https://www.mdpi.com/1999-4923/14/6/1159

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