Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats

<p>Abstract</p> <p>Background</p> <p>The <it>Orf virus </it>(ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic...

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Main Authors: Cvetnic Zeljko, Bedekovic Tomislav, Beck Ana, Cac Zeljko, Lojkic Ivana, Sostaric Branko
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/314
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author Cvetnic Zeljko
Bedekovic Tomislav
Beck Ana
Cac Zeljko
Lojkic Ivana
Sostaric Branko
author_facet Cvetnic Zeljko
Bedekovic Tomislav
Beck Ana
Cac Zeljko
Lojkic Ivana
Sostaric Branko
author_sort Cvetnic Zeljko
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>The <it>Orf virus </it>(ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochthonous Croatian Cres-breed sheep and ii) on small family goat farm.</p> <p>Results</p> <p>Sequence and phylogenetic analyses of the ORFV B2L gene showed that the Cro-Cres-12446/09 and Cro-Goat-11727/10 were not clustered together. Cro-Cres-12446/09 shared the highest similarity with ORFV NZ2 from New Zealand, and Ena from Japan; Cro-Goat-11727/10 was closest to the HuB from China and Taiping and Hoping from Taiwan.</p> <p>Conclusion</p> <p>Distinct ORFV strains are circulating in Croatia. Although ORFV infections are found ubiquitously wherever sheep and goats are farmed in Croatia, this is the first information on genetic relatedness of any Croatian ORFV with other isolates around the world.</p>
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spelling doaj.art-ba6b61072b124574b2b3fd9e3a4e1b932022-12-22T03:28:33ZengBMCVirology Journal1743-422X2010-11-017131410.1186/1743-422X-7-314Phylogenetic analysis of Croatian orf viruses isolated from sheep and goatsCvetnic ZeljkoBedekovic TomislavBeck AnaCac ZeljkoLojkic IvanaSostaric Branko<p>Abstract</p> <p>Background</p> <p>The <it>Orf virus </it>(ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochthonous Croatian Cres-breed sheep and ii) on small family goat farm.</p> <p>Results</p> <p>Sequence and phylogenetic analyses of the ORFV B2L gene showed that the Cro-Cres-12446/09 and Cro-Goat-11727/10 were not clustered together. Cro-Cres-12446/09 shared the highest similarity with ORFV NZ2 from New Zealand, and Ena from Japan; Cro-Goat-11727/10 was closest to the HuB from China and Taiping and Hoping from Taiwan.</p> <p>Conclusion</p> <p>Distinct ORFV strains are circulating in Croatia. Although ORFV infections are found ubiquitously wherever sheep and goats are farmed in Croatia, this is the first information on genetic relatedness of any Croatian ORFV with other isolates around the world.</p>http://www.virologyj.com/content/7/1/314
spellingShingle Cvetnic Zeljko
Bedekovic Tomislav
Beck Ana
Cac Zeljko
Lojkic Ivana
Sostaric Branko
Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
Virology Journal
title Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_full Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_fullStr Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_full_unstemmed Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_short Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_sort phylogenetic analysis of croatian orf viruses isolated from sheep and goats
url http://www.virologyj.com/content/7/1/314
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AT bedekovictomislav phylogeneticanalysisofcroatianorfvirusesisolatedfromsheepandgoats
AT beckana phylogeneticanalysisofcroatianorfvirusesisolatedfromsheepandgoats
AT caczeljko phylogeneticanalysisofcroatianorfvirusesisolatedfromsheepandgoats
AT lojkicivana phylogeneticanalysisofcroatianorfvirusesisolatedfromsheepandgoats
AT sostaricbranko phylogeneticanalysisofcroatianorfvirusesisolatedfromsheepandgoats