MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS

The paper describes a clinical case of adverse reaction (AR) to leflunomide (LEF) in a female patient with rheumatoid arthritis (RA). In 2007 to 2017, the female patient with a reliable diagnosis of RA took LEF (Arava) at a dose of 20 mg/day, which showed a good clinical effect. However, the patient...

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Main Authors: L. I. Alekseeva, N. G. Kashevarova, E. A. Taskina, Ya. A. Sigidin
Format: Article
Language:Russian
Published: IMA PRESS LLC 2018-11-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/2632
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author L. I. Alekseeva
N. G. Kashevarova
E. A. Taskina
Ya. A. Sigidin
author_facet L. I. Alekseeva
N. G. Kashevarova
E. A. Taskina
Ya. A. Sigidin
author_sort L. I. Alekseeva
collection DOAJ
description The paper describes a clinical case of adverse reaction (AR) to leflunomide (LEF) in a female patient with rheumatoid arthritis (RA). In 2007 to 2017, the female patient with a reliable diagnosis of RA took LEF (Arava) at a dose of 20 mg/day, which showed a good clinical effect. However, the patient developed atypical bone cysts in the hands, feet, right elbow, and left heel 10 years after start of therapy. The differential diagnosis with deep mycosis, tuberculosis, cancer pathology, endocrine system disease, and AR to the long-term use of LEF was made to clarify the nature of bone cysts.
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spelling doaj.art-ba6f6a34e3b1437391f852e5bcaf9ea52023-03-22T13:45:54ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922018-11-0156566166610.14412/1995-4484-2018-661-6662415MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITISL. I. Alekseeva0N. G. Kashevarova1E. A. Taskina2Ya. A. Sigidin3V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyThe paper describes a clinical case of adverse reaction (AR) to leflunomide (LEF) in a female patient with rheumatoid arthritis (RA). In 2007 to 2017, the female patient with a reliable diagnosis of RA took LEF (Arava) at a dose of 20 mg/day, which showed a good clinical effect. However, the patient developed atypical bone cysts in the hands, feet, right elbow, and left heel 10 years after start of therapy. The differential diagnosis with deep mycosis, tuberculosis, cancer pathology, endocrine system disease, and AR to the long-term use of LEF was made to clarify the nature of bone cysts.https://rsp.mediar-press.net/rsp/article/view/2632leflunomideadverse reactionbone cystsdifferential diagnosis of bone cysts
spellingShingle L. I. Alekseeva
N. G. Kashevarova
E. A. Taskina
Ya. A. Sigidin
MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
Научно-практическая ревматология
leflunomide
adverse reaction
bone cysts
differential diagnosis of bone cysts
title MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
title_full MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
title_fullStr MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
title_full_unstemmed MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
title_short MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
title_sort multiple bone cysts caused by the intake of leflunomide in a female patient with rheumatoid arthritis
topic leflunomide
adverse reaction
bone cysts
differential diagnosis of bone cysts
url https://rsp.mediar-press.net/rsp/article/view/2632
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AT ngkashevarova multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis
AT eataskina multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis
AT yaasigidin multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis