MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS
The paper describes a clinical case of adverse reaction (AR) to leflunomide (LEF) in a female patient with rheumatoid arthritis (RA). In 2007 to 2017, the female patient with a reliable diagnosis of RA took LEF (Arava) at a dose of 20 mg/day, which showed a good clinical effect. However, the patient...
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Format: | Article |
Language: | Russian |
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IMA PRESS LLC
2018-11-01
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Series: | Научно-практическая ревматология |
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Online Access: | https://rsp.mediar-press.net/rsp/article/view/2632 |
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author | L. I. Alekseeva N. G. Kashevarova E. A. Taskina Ya. A. Sigidin |
author_facet | L. I. Alekseeva N. G. Kashevarova E. A. Taskina Ya. A. Sigidin |
author_sort | L. I. Alekseeva |
collection | DOAJ |
description | The paper describes a clinical case of adverse reaction (AR) to leflunomide (LEF) in a female patient with rheumatoid arthritis (RA). In 2007 to 2017, the female patient with a reliable diagnosis of RA took LEF (Arava) at a dose of 20 mg/day, which showed a good clinical effect. However, the patient developed atypical bone cysts in the hands, feet, right elbow, and left heel 10 years after start of therapy. The differential diagnosis with deep mycosis, tuberculosis, cancer pathology, endocrine system disease, and AR to the long-term use of LEF was made to clarify the nature of bone cysts. |
first_indexed | 2024-04-09T22:23:21Z |
format | Article |
id | doaj.art-ba6f6a34e3b1437391f852e5bcaf9ea5 |
institution | Directory Open Access Journal |
issn | 1995-4484 1995-4492 |
language | Russian |
last_indexed | 2024-04-09T22:23:21Z |
publishDate | 2018-11-01 |
publisher | IMA PRESS LLC |
record_format | Article |
series | Научно-практическая ревматология |
spelling | doaj.art-ba6f6a34e3b1437391f852e5bcaf9ea52023-03-22T13:45:54ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922018-11-0156566166610.14412/1995-4484-2018-661-6662415MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITISL. I. Alekseeva0N. G. Kashevarova1E. A. Taskina2Ya. A. Sigidin3V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyThe paper describes a clinical case of adverse reaction (AR) to leflunomide (LEF) in a female patient with rheumatoid arthritis (RA). In 2007 to 2017, the female patient with a reliable diagnosis of RA took LEF (Arava) at a dose of 20 mg/day, which showed a good clinical effect. However, the patient developed atypical bone cysts in the hands, feet, right elbow, and left heel 10 years after start of therapy. The differential diagnosis with deep mycosis, tuberculosis, cancer pathology, endocrine system disease, and AR to the long-term use of LEF was made to clarify the nature of bone cysts.https://rsp.mediar-press.net/rsp/article/view/2632leflunomideadverse reactionbone cystsdifferential diagnosis of bone cysts |
spellingShingle | L. I. Alekseeva N. G. Kashevarova E. A. Taskina Ya. A. Sigidin MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS Научно-практическая ревматология leflunomide adverse reaction bone cysts differential diagnosis of bone cysts |
title | MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS |
title_full | MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS |
title_fullStr | MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS |
title_full_unstemmed | MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS |
title_short | MULTIPLE BONE CYSTS CAUSED BY THE INTAKE OF LEFLUNOMIDE IN A FEMALE PATIENT WITH RHEUMATOID ARTHRITIS |
title_sort | multiple bone cysts caused by the intake of leflunomide in a female patient with rheumatoid arthritis |
topic | leflunomide adverse reaction bone cysts differential diagnosis of bone cysts |
url | https://rsp.mediar-press.net/rsp/article/view/2632 |
work_keys_str_mv | AT lialekseeva multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis AT ngkashevarova multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis AT eataskina multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis AT yaasigidin multiplebonecystscausedbytheintakeofleflunomideinafemalepatientwithrheumatoidarthritis |