Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control?
ObjectiveThe requirement of a chronic treatment and the increase in life expectancy in children with type 1 diabetes (T1D) leads to the possibility of caregiver burden. The aim of our study was to evaluate the burden in primary informal caregivers (PIC) of children and adolescents with type 1 diabet...
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| Format: | Article |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1089160/full |
| _version_ | 1797948196385718272 |
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| author | Lourdes Balcázar-Hernández Hebert Huerta-Martínez Eulalia Garrido Magaña Elisa Nishimura-Meguro Abigail Jiménez Márquez Aleida Rivera-Hernández |
| author_facet | Lourdes Balcázar-Hernández Hebert Huerta-Martínez Eulalia Garrido Magaña Elisa Nishimura-Meguro Abigail Jiménez Márquez Aleida Rivera-Hernández |
| author_sort | Lourdes Balcázar-Hernández |
| collection | DOAJ |
| description | ObjectiveThe requirement of a chronic treatment and the increase in life expectancy in children with type 1 diabetes (T1D) leads to the possibility of caregiver burden. The aim of our study was to evaluate the burden in primary informal caregivers (PIC) of children and adolescents with type 1 diabetes and its association with depression, family dysfunction, and glycemic control.Materials and methodsA retrospective study was performed in PIC of children and adolescents with T1D. Zarit Burden Interview Scale (ZBIS) was used to evaluate caregiver burden. Beck Depression Inventory (BDI-II) was used to evaluate depression in PIC, and the Family APGAR questionnaire was used to evaluate the family functionality.ResultsA total of 100 PIC of children and adolescents with T1D were included. Caregiver burden was found in 33% of caregivers. The total score of the Zarit scale was 41 (34–49); 19% had mild caregiver burden, and 14% had severe caregiver burden. According to the BDI-II, 82% had minimal depression, 11% mild depression, 5% moderate depression, and 2% severe depression. Family function was good in 69%; 13% had moderate dysfunction, and 18% had severe dysfunction. A positive correlation between caregiver burden and BDI-II score (r = 0.84; p = 0.001) and the grade of depression (r = 0.87; p = 0.001) was found. A logistic regression model showed that BDI-II score was associated with caregiver burden (OR 1.14; 95% CI 1.061–1.23; p = 0.001). A BDI-II cut off of 9 or more had a sensibility and specificity of 58% and 28%, respectively, for caregiver burden [AUC 0.751 (0.64–0.85); p = 0.001]. A BDI-II score ≥9 was a predictor of caregiver burden (OR 3.4; 95% CI 1.4–8.1; p = 0.008).ConclusionCaregiver burden is present in more than one third of the PIC of patients with T1D and is associated with depression. A BDI-II score ≥9 is a predictor of caregiver burden which may be a point to take into account in the integral approach to the patient with T1D and his or her family nucleus. |
| first_indexed | 2024-04-10T21:40:41Z |
| format | Article |
| id | doaj.art-ba72c279f98d4026a29ee4a669e35ba8 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-10T21:40:41Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-ba72c279f98d4026a29ee4a669e35ba82023-01-19T05:59:30ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-01-011310.3389/fendo.2022.10891601089160Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control?Lourdes Balcázar-Hernández0Hebert Huerta-Martínez1Eulalia Garrido Magaña2Elisa Nishimura-Meguro3Abigail Jiménez Márquez4Aleida Rivera-Hernández5Endocrinology Department, Hospital de Especialidades, Unidad Médica de Alta Especialidad (UMAE) Centro Médico Nacional Siglo XXI, Mexico City, MexicoPediatric Endocrinology Department, Hospital de Pediatría, Unidad Médica de Alta Especialidad Centro Médico Nacional Siglo XXI, Mexico City, MexicoPediatric Endocrinology Department, Hospital de Pediatría, Unidad Médica de Alta Especialidad Centro Médico Nacional Siglo XXI, Mexico City, MexicoPediatric Endocrinology Department, Hospital de Pediatría, Unidad Médica de Alta Especialidad Centro Médico Nacional Siglo XXI, Mexico City, MexicoPediatric Endocrinology Department, Hospital de Pediatría, Unidad Médica de Alta Especialidad Centro Médico Nacional Siglo XXI, Mexico City, MexicoPediatric Endocrinology Department, Hospital de Pediatría, Unidad Médica de Alta Especialidad Centro Médico Nacional Siglo XXI, Mexico City, MexicoObjectiveThe requirement of a chronic treatment and the increase in life expectancy in children with type 1 diabetes (T1D) leads to the possibility of caregiver burden. The aim of our study was to evaluate the burden in primary informal caregivers (PIC) of children and adolescents with type 1 diabetes and its association with depression, family dysfunction, and glycemic control.Materials and methodsA retrospective study was performed in PIC of children and adolescents with T1D. Zarit Burden Interview Scale (ZBIS) was used to evaluate caregiver burden. Beck Depression Inventory (BDI-II) was used to evaluate depression in PIC, and the Family APGAR questionnaire was used to evaluate the family functionality.ResultsA total of 100 PIC of children and adolescents with T1D were included. Caregiver burden was found in 33% of caregivers. The total score of the Zarit scale was 41 (34–49); 19% had mild caregiver burden, and 14% had severe caregiver burden. According to the BDI-II, 82% had minimal depression, 11% mild depression, 5% moderate depression, and 2% severe depression. Family function was good in 69%; 13% had moderate dysfunction, and 18% had severe dysfunction. A positive correlation between caregiver burden and BDI-II score (r = 0.84; p = 0.001) and the grade of depression (r = 0.87; p = 0.001) was found. A logistic regression model showed that BDI-II score was associated with caregiver burden (OR 1.14; 95% CI 1.061–1.23; p = 0.001). A BDI-II cut off of 9 or more had a sensibility and specificity of 58% and 28%, respectively, for caregiver burden [AUC 0.751 (0.64–0.85); p = 0.001]. A BDI-II score ≥9 was a predictor of caregiver burden (OR 3.4; 95% CI 1.4–8.1; p = 0.008).ConclusionCaregiver burden is present in more than one third of the PIC of patients with T1D and is associated with depression. A BDI-II score ≥9 is a predictor of caregiver burden which may be a point to take into account in the integral approach to the patient with T1D and his or her family nucleus.https://www.frontiersin.org/articles/10.3389/fendo.2022.1089160/fulltype 1 diabetes mellituscaregiver burdenprimary informal caregiversdepressionfamily dysfunction |
| spellingShingle | Lourdes Balcázar-Hernández Hebert Huerta-Martínez Eulalia Garrido Magaña Elisa Nishimura-Meguro Abigail Jiménez Márquez Aleida Rivera-Hernández Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control? Frontiers in Endocrinology type 1 diabetes mellitus caregiver burden primary informal caregivers depression family dysfunction |
| title | Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control? |
| title_full | Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control? |
| title_fullStr | Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control? |
| title_full_unstemmed | Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control? |
| title_short | Burden in primary informal caregivers of children and adolescents with type 1 diabetes: Is it associated with depression, family dysfunction, and glycemic control? |
| title_sort | burden in primary informal caregivers of children and adolescents with type 1 diabetes is it associated with depression family dysfunction and glycemic control |
| topic | type 1 diabetes mellitus caregiver burden primary informal caregivers depression family dysfunction |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.1089160/full |
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