Urinary protein biomarkers based on LC–MS/MS analysis to discriminate vascular dementia from Alzheimer’s disease in Han Chinese population

Urinary protein biomarkers based on LC–MS/MS analysis to discriminate vascular dementia from Alzheimer’s disease in Han Chinese population

ObjectiveThis study aimed to identify the potential urine biomarkers of vascular dementia (VD) and unravel the disease-associated mechanisms by applying Liquid chromatography tandem-mass spectrometry (LC–MS/MS).MethodsLC–MS/MS proteomic analysis was applied to urine samples from 3 groups, including...

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Bibliographic Details
Main Authors: Ruijuan Chen, Yuanjing Yi, Wenbiao Xiao, Bowen Zhong, Le Zhang, Yi Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
vascular dementia
Alzheimer’s disease
biomarkers
urine
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1070854/full

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