A cell-based in vitro assay for testing of immunological integrity of Tetanus toxoid vaccine antigen
Abstract Vaccines containing inactivated toxins confer protection by eliciting a neutralizing antibody response against bacterial toxins such as tetanus and diphtheria. At present, release of tetanus toxoid (TT) and diphtheria toxoid (DT)-containing vaccines relies on in vivo experiments showing the...
Main Authors: | Olga Ticha, Dido Klemm, Lukas Moos, Isabelle Bekeredjian-Ding |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-06-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-021-00344-1 |
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