Potential Regulatory Roles of GRK2 in Endothelial Cell Activity and Pathological Angiogenesis

Potential Regulatory Roles of GRK2 in Endothelial Cell Activity and Pathological Angiogenesis

G protein-coupled receptor (GPCR) kinase 2 (GRK2) is an integrative node in many signaling network cascades. Emerging evidence indicates that GRK2 can interact with a large number of GPCRs and non-GPCR substrates in both kinase-dependent and -independent modes. Some of these pathways are associated...

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Bibliographic Details
Main Authors: Jiajie Kuai, Chenchen Han, Wei Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
GRK2
GPCRs
endothelial cells
activity
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.698424/full

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