A New Era of Prostate Cancer Precision Medicine
Prostate cancer is the second most common male cancer affecting Western society. Despite substantial advances in the exploration of prostate cancer biomarkers and treatment strategies, men are over diagnosed with inert prostate cancer, while there is also a substantial mortality from the invasive di...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-11-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2019.01263/full |
| _version_ | 1818899630645051392 |
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| author | Adil Malik Adil Malik Srilakshmi Srinivasan Srilakshmi Srinivasan Jyotsna Batra Jyotsna Batra |
| author_facet | Adil Malik Adil Malik Srilakshmi Srinivasan Srilakshmi Srinivasan Jyotsna Batra Jyotsna Batra |
| author_sort | Adil Malik |
| collection | DOAJ |
| description | Prostate cancer is the second most common male cancer affecting Western society. Despite substantial advances in the exploration of prostate cancer biomarkers and treatment strategies, men are over diagnosed with inert prostate cancer, while there is also a substantial mortality from the invasive disease. Precision medicine is the management of treatment profiles across different cancers predicting therapies for individual cancer patients. With strategies including individual genomic profiling and targeting specific cancer pathways, precision medicine for prostate cancer has the potential to impose changes in clinical practices. Some of the recent advances in prostate cancer precision medicine comprise targeting gene fusions, genome editing tools, non-coding RNA biomarkers, and the promise of liquid tumor profiling. In this review, we will discuss these recent scientific advances to scale up these approaches and endeavors to overcome clinical barriers for prostate cancer precision medicine. |
| first_indexed | 2024-12-19T19:51:01Z |
| format | Article |
| id | doaj.art-ba7f869462044ae2b39f361bd7b1c0cd |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-19T19:51:01Z |
| publishDate | 2019-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-ba7f869462044ae2b39f361bd7b1c0cd2022-12-21T20:08:00ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2019-11-01910.3389/fonc.2019.01263476911A New Era of Prostate Cancer Precision MedicineAdil Malik0Adil Malik1Srilakshmi Srinivasan2Srilakshmi Srinivasan3Jyotsna Batra4Jyotsna Batra5School of Biomedical Sciences, Queensland University of Technology, Institute of Health and Biomedical Innovation, Brisbane, QLD, AustraliaAustralian Prostate Cancer Research Centre–Queensland, Translational Research Institute, Woolloongabba, QLD, AustraliaSchool of Biomedical Sciences, Queensland University of Technology, Institute of Health and Biomedical Innovation, Brisbane, QLD, AustraliaAustralian Prostate Cancer Research Centre–Queensland, Translational Research Institute, Woolloongabba, QLD, AustraliaSchool of Biomedical Sciences, Queensland University of Technology, Institute of Health and Biomedical Innovation, Brisbane, QLD, AustraliaAustralian Prostate Cancer Research Centre–Queensland, Translational Research Institute, Woolloongabba, QLD, AustraliaProstate cancer is the second most common male cancer affecting Western society. Despite substantial advances in the exploration of prostate cancer biomarkers and treatment strategies, men are over diagnosed with inert prostate cancer, while there is also a substantial mortality from the invasive disease. Precision medicine is the management of treatment profiles across different cancers predicting therapies for individual cancer patients. With strategies including individual genomic profiling and targeting specific cancer pathways, precision medicine for prostate cancer has the potential to impose changes in clinical practices. Some of the recent advances in prostate cancer precision medicine comprise targeting gene fusions, genome editing tools, non-coding RNA biomarkers, and the promise of liquid tumor profiling. In this review, we will discuss these recent scientific advances to scale up these approaches and endeavors to overcome clinical barriers for prostate cancer precision medicine.https://www.frontiersin.org/article/10.3389/fonc.2019.01263/fullprostate cancerprecision medicinegene fusionbiomarkersproteomic technologiesgenome editing |
| spellingShingle | Adil Malik Adil Malik Srilakshmi Srinivasan Srilakshmi Srinivasan Jyotsna Batra Jyotsna Batra A New Era of Prostate Cancer Precision Medicine Frontiers in Oncology prostate cancer precision medicine gene fusion biomarkers proteomic technologies genome editing |
| title | A New Era of Prostate Cancer Precision Medicine |
| title_full | A New Era of Prostate Cancer Precision Medicine |
| title_fullStr | A New Era of Prostate Cancer Precision Medicine |
| title_full_unstemmed | A New Era of Prostate Cancer Precision Medicine |
| title_short | A New Era of Prostate Cancer Precision Medicine |
| title_sort | new era of prostate cancer precision medicine |
| topic | prostate cancer precision medicine gene fusion biomarkers proteomic technologies genome editing |
| url | https://www.frontiersin.org/article/10.3389/fonc.2019.01263/full |
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