Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information
Abstract The misinformation effect occurs when people’s memory of an event is altered by subsequent inaccurate information. No study has systematically tested theories about the dynamics of human hippocampal representations during the three stages of misinformation-induced false memory. This study r...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-38046-y |
| _version_ | 1797840952629395456 |
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| author | Xuhao Shao Ao Li Chuansheng Chen Elizabeth F. Loftus Bi Zhu |
| author_facet | Xuhao Shao Ao Li Chuansheng Chen Elizabeth F. Loftus Bi Zhu |
| author_sort | Xuhao Shao |
| collection | DOAJ |
| description | Abstract The misinformation effect occurs when people’s memory of an event is altered by subsequent inaccurate information. No study has systematically tested theories about the dynamics of human hippocampal representations during the three stages of misinformation-induced false memory. This study replicates behavioral results of the misinformation effect, and investigates the cross-stage pattern similarity in the hippocampus and cortex using functional magnetic resonance imaging. Results show item-specific hippocampal pattern similarity between original-event and post-event stages. During the memory-test stage, hippocampal representations of original information are weakened for true memory, whereas hippocampal representations of misinformation compete with original information to create false memory. When false memory occurs, this conflict is resolved by the lateral prefrontal cortex. Individuals’ memory traces of post-event information in the hippocampus predict false memory, whereas original information in the lateral parietal cortex predicts true memory. These findings support the multiple-trace model, and emphasize the reconstructive nature of human memory. |
| first_indexed | 2024-04-09T16:23:09Z |
| format | Article |
| id | doaj.art-ba848eba1402469b83addf5191766a3a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T16:23:09Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-ba848eba1402469b83addf5191766a3a2023-04-23T11:21:45ZengNature PortfolioNature Communications2041-17232023-04-0114111410.1038/s41467-023-38046-yCross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate informationXuhao Shao0Ao Li1Chuansheng Chen2Elizabeth F. Loftus3Bi Zhu4State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal UniversityState Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal UniversityDepartment of Psychological Science, University of CaliforniaDepartment of Psychological Science, University of CaliforniaState Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal UniversityAbstract The misinformation effect occurs when people’s memory of an event is altered by subsequent inaccurate information. No study has systematically tested theories about the dynamics of human hippocampal representations during the three stages of misinformation-induced false memory. This study replicates behavioral results of the misinformation effect, and investigates the cross-stage pattern similarity in the hippocampus and cortex using functional magnetic resonance imaging. Results show item-specific hippocampal pattern similarity between original-event and post-event stages. During the memory-test stage, hippocampal representations of original information are weakened for true memory, whereas hippocampal representations of misinformation compete with original information to create false memory. When false memory occurs, this conflict is resolved by the lateral prefrontal cortex. Individuals’ memory traces of post-event information in the hippocampus predict false memory, whereas original information in the lateral parietal cortex predicts true memory. These findings support the multiple-trace model, and emphasize the reconstructive nature of human memory.https://doi.org/10.1038/s41467-023-38046-y |
| spellingShingle | Xuhao Shao Ao Li Chuansheng Chen Elizabeth F. Loftus Bi Zhu Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information Nature Communications |
| title | Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information |
| title_full | Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information |
| title_fullStr | Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information |
| title_full_unstemmed | Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information |
| title_short | Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information |
| title_sort | cross stage neural pattern similarity in the hippocampus predicts false memory derived from post event inaccurate information |
| url | https://doi.org/10.1038/s41467-023-38046-y |
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