Retrospective analysis of acute HBV infections occurred in 1978–79 and 1994–95 in North-East Italy: increasing prevalence of BCP/pre-core mutants in sub-genotype D3

Retrospective analysis of acute HBV infections occurred in 1978–79 and 1994–95 in North-East Italy: increasing prevalence of BCP/pre-core mutants in sub-genotype D3

Abstract Background At the end of the 1970s, in Italy more than 2% of the general population was HBsAg carrier. In the late ‘70s and late ‘80s, two remarkable events might have impacted on HBV strains transmitted in North-East Italy: (a) the increased HBV incidence due to parenteral drugs between 19...

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Bibliographic Details
Main Authors: Roberto Bruni, Umbertina Villano, Stefania Taffon, Michele Equestre, Elisabetta Madonna, Paola Chionne, Angela Candido, Stefano Dettori, Giulio Pisani, Maria Rapicetta, Flavia Bortolotti, Anna Rita Ciccaglione
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Infectious Diseases
Subjects:
Hepatitis B virus
HBV
Genotype
Sub-genotype
Basal core promoter
Pre-core
Online Access:https://doi.org/10.1186/s12879-019-4713-9

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