Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study
Unstable carotid plaques are visualized as high-signal plaques (HSPs) on 3D turbo spin-echo T1-weighted black-blood vessel wall imaging (3D TSE T1-BB VWI). The purpose of this study was to compare manual segmentation and semiautomated segmentation for the quantification of carotid HSPs using 3D TSE...
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MDPI AG
2022-04-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/4/1014 |
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| author | Katsuhiro Inoue Ryohei Nakayama Shiho Isoshima Shinichi Takase Tsunehiro Yamahata Maki Umino Masayuki Maeda Hajime Sakuma |
| author_facet | Katsuhiro Inoue Ryohei Nakayama Shiho Isoshima Shinichi Takase Tsunehiro Yamahata Maki Umino Masayuki Maeda Hajime Sakuma |
| author_sort | Katsuhiro Inoue |
| collection | DOAJ |
| description | Unstable carotid plaques are visualized as high-signal plaques (HSPs) on 3D turbo spin-echo T1-weighted black-blood vessel wall imaging (3D TSE T1-BB VWI). The purpose of this study was to compare manual segmentation and semiautomated segmentation for the quantification of carotid HSPs using 3D TSE T1-BB VWI. Twenty cervical carotid plaque lesions in 19 patients with a plaque contrast ratio of > 1.3 compared to adjacent muscle were studied. Using the mean voxel value for the adjacent muscle multiplied by 1.3 as a threshold value, the semiautomated software exclusively segmented and measured the HSP volume. Manual and semiautomated HSP volumes were well correlated (r = 0.965). Regarding reproducibility, the inter-rater ICC was 0.959 (bias: 24.63, 95% limit of agreement: −96.07, 146.35) for the manual method and 0.998 (bias: 15.2, 95% limit of agreement: −17.83, 48.23) for the semiautomated method, indicating improved reproducibility by the semiautomated method compared to the manual method. The time required for semiautomated segmentation was significantly shorter than that of manual segmentation times (81.7 ± 7.8 s versus 189.5 ± 49.6 s; <i>p</i> < 0.01). The results obtained in this study demonstrate that the semiautomated segmentation method allows for reliable assessment of the HSP volume in patients with carotid plaque lesions, with reduced time and effort for the analysis. |
| first_indexed | 2024-03-09T10:56:36Z |
| format | Article |
| id | doaj.art-ba84bf82b64b40d38a55da45b8bfba76 |
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| language | English |
| last_indexed | 2024-03-09T10:56:36Z |
| publishDate | 2022-04-01 |
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| series | Diagnostics |
| spelling | doaj.art-ba84bf82b64b40d38a55da45b8bfba762023-12-01T01:38:13ZengMDPI AGDiagnostics2075-44182022-04-01124101410.3390/diagnostics12041014Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary StudyKatsuhiro Inoue0Ryohei Nakayama1Shiho Isoshima2Shinichi Takase3Tsunehiro Yamahata4Maki Umino5Masayuki Maeda6Hajime Sakuma7Department of Radiology, Mie University Hospital, Tsu 514-8507, Mie, JapanDepartment of Electronic and Computer Engineering, Ritsumeikan University, Kusatsu 525-8577, Shiga, JapanDepartment of Radiology, Mie University Hospital, Tsu 514-8507, Mie, JapanDepartment of Radiology, Mie University Hospital, Tsu 514-8507, Mie, JapanDepartment of Radiology, Mie University Hospital, Tsu 514-8507, Mie, JapanDepartment of Radiology, Mie University School of Medicine, Tsu 514-8507, Mie, JapanDepartment of Neuroradiology, Mie University School of Medicine, Tsu 514-8507, Mie, JapanDepartment of Radiology, Mie University School of Medicine, Tsu 514-8507, Mie, JapanUnstable carotid plaques are visualized as high-signal plaques (HSPs) on 3D turbo spin-echo T1-weighted black-blood vessel wall imaging (3D TSE T1-BB VWI). The purpose of this study was to compare manual segmentation and semiautomated segmentation for the quantification of carotid HSPs using 3D TSE T1-BB VWI. Twenty cervical carotid plaque lesions in 19 patients with a plaque contrast ratio of > 1.3 compared to adjacent muscle were studied. Using the mean voxel value for the adjacent muscle multiplied by 1.3 as a threshold value, the semiautomated software exclusively segmented and measured the HSP volume. Manual and semiautomated HSP volumes were well correlated (r = 0.965). Regarding reproducibility, the inter-rater ICC was 0.959 (bias: 24.63, 95% limit of agreement: −96.07, 146.35) for the manual method and 0.998 (bias: 15.2, 95% limit of agreement: −17.83, 48.23) for the semiautomated method, indicating improved reproducibility by the semiautomated method compared to the manual method. The time required for semiautomated segmentation was significantly shorter than that of manual segmentation times (81.7 ± 7.8 s versus 189.5 ± 49.6 s; <i>p</i> < 0.01). The results obtained in this study demonstrate that the semiautomated segmentation method allows for reliable assessment of the HSP volume in patients with carotid plaque lesions, with reduced time and effort for the analysis.https://www.mdpi.com/2075-4418/12/4/1014carotid arteryunstable carotid plaquesemiautomated segmentation3D TSE T1-weighted black-blood vessel wall imaging |
| spellingShingle | Katsuhiro Inoue Ryohei Nakayama Shiho Isoshima Shinichi Takase Tsunehiro Yamahata Maki Umino Masayuki Maeda Hajime Sakuma Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study Diagnostics carotid artery unstable carotid plaque semiautomated segmentation 3D TSE T1-weighted black-blood vessel wall imaging |
| title | Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study |
| title_full | Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study |
| title_fullStr | Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study |
| title_full_unstemmed | Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study |
| title_short | Semiautomated Segmentation and Volume Measurements of Cervical Carotid High-Signal Plaques Using 3D Turbo Spin-Echo T1-Weighted Black-Blood Vessel Wall Imaging: A Preliminary Study |
| title_sort | semiautomated segmentation and volume measurements of cervical carotid high signal plaques using 3d turbo spin echo t1 weighted black blood vessel wall imaging a preliminary study |
| topic | carotid artery unstable carotid plaque semiautomated segmentation 3D TSE T1-weighted black-blood vessel wall imaging |
| url | https://www.mdpi.com/2075-4418/12/4/1014 |
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