Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women
Thrombophilia, blood clotting abnormalities that increase the risk of thrombosis, can be inherited (congenital thrombophilia) or acquired during life. We conducted a study using the questionnaire method, which included 38 questions. The questionnaire was posted on social media groups dedicated to pa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2020-12-01
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| Series: | Romanian Journal of Medical Practice |
| Subjects: | |
| Online Access: | https://rjmp.com.ro/articles/2020.4/RJMP_2020_4_Art-13.pdf |
| _version_ | 1818590427648884736 |
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| author | Mohammed Bashir MADALAH Eduard CIRCO Maria ŞUŢA Cătălin GRIGORE Bogdan CIORNEI |
| author_facet | Mohammed Bashir MADALAH Eduard CIRCO Maria ŞUŢA Cătălin GRIGORE Bogdan CIORNEI |
| author_sort | Mohammed Bashir MADALAH |
| collection | DOAJ |
| description | Thrombophilia, blood clotting abnormalities that increase the risk of thrombosis, can be inherited (congenital thrombophilia) or acquired during life. We conducted a study using the questionnaire method, which included 38 questions. The questionnaire was posted on social media groups dedicated to patients with thrombophilia in Romania. 99 patients responded to our request to complete the questionnaire, 91 performed tests for the diagnosis of thrombophilia and 85 were diagnosed with thrombophilia (81 diagnosed with inherited thrombophilia, 1 with acquired thrombophilia and 3 with mixed thrombophilia). It was shown that, in our group, the most common inherited thrombophilias are the factor V mutation (FVL) and the MTHFR gene mutation, in over 95% of cases.
The results of the study may be a starting point for larger batch studies on the presence of genetic mutations in patients with inherited thrombophilia, to more effectively prevent pregnancy complications. |
| first_indexed | 2024-12-16T09:56:22Z |
| format | Article |
| id | doaj.art-ba85cac11340479f99151fdb2f8e54f9 |
| institution | Directory Open Access Journal |
| issn | 1842-8258 2069-6108 |
| language | English |
| last_indexed | 2024-12-16T09:56:22Z |
| publishDate | 2020-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Medical Practice |
| spelling | doaj.art-ba85cac11340479f99151fdb2f8e54f92022-12-21T22:35:54ZengAmaltea Medical Publishing HouseRomanian Journal of Medical Practice1842-82582069-61082020-12-0115443444010.37897/RJMP.2020.4.13Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant womenMohammed Bashir MADALAH0Eduard CIRCO1Maria ŞUŢA2Cătălin GRIGORE3Bogdan CIORNEI4Universitatea „Ovidius“, Constanța, RomâniaUniversitatea „Ovidius“, Constanța, RomâniaUniversitatea „Ovidius“, Constanța, RomâniaClinica Aqua, Constanța, RomâniaSpital Privat Isis, Constanța, RomâniaThrombophilia, blood clotting abnormalities that increase the risk of thrombosis, can be inherited (congenital thrombophilia) or acquired during life. We conducted a study using the questionnaire method, which included 38 questions. The questionnaire was posted on social media groups dedicated to patients with thrombophilia in Romania. 99 patients responded to our request to complete the questionnaire, 91 performed tests for the diagnosis of thrombophilia and 85 were diagnosed with thrombophilia (81 diagnosed with inherited thrombophilia, 1 with acquired thrombophilia and 3 with mixed thrombophilia). It was shown that, in our group, the most common inherited thrombophilias are the factor V mutation (FVL) and the MTHFR gene mutation, in over 95% of cases. The results of the study may be a starting point for larger batch studies on the presence of genetic mutations in patients with inherited thrombophilia, to more effectively prevent pregnancy complications.https://rjmp.com.ro/articles/2020.4/RJMP_2020_4_Art-13.pdfinherited thrombophiliapregnancy complicationsthromboembolic eventsrecurrent pregnancy lossthromboprophylaxis |
| spellingShingle | Mohammed Bashir MADALAH Eduard CIRCO Maria ŞUŢA Cătălin GRIGORE Bogdan CIORNEI Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women Romanian Journal of Medical Practice inherited thrombophilia pregnancy complications thromboembolic events recurrent pregnancy loss thromboprophylaxis |
| title | Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women |
| title_full | Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women |
| title_fullStr | Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women |
| title_full_unstemmed | Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women |
| title_short | Inherited thrombophilia in pregnancy. Study by questionnaire method in a group of pregnant women |
| title_sort | inherited thrombophilia in pregnancy study by questionnaire method in a group of pregnant women |
| topic | inherited thrombophilia pregnancy complications thromboembolic events recurrent pregnancy loss thromboprophylaxis |
| url | https://rjmp.com.ro/articles/2020.4/RJMP_2020_4_Art-13.pdf |
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