A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications

Bioactive glasses (BGs) are traditionally known to be able to bond to living bone and stimulate bone regeneration. The production of such materials in a mesoporous form allowed scientists to dramatically expand the versatility of oxide-based glass systems as well as their applications in biomedicine...

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Main Authors: Carla Migneco, Elisa Fiume, Enrica Verné, Francesco Baino
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/10/12/2571
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author Carla Migneco
Elisa Fiume
Enrica Verné
Francesco Baino
author_facet Carla Migneco
Elisa Fiume
Enrica Verné
Francesco Baino
author_sort Carla Migneco
collection DOAJ
description Bioactive glasses (BGs) are traditionally known to be able to bond to living bone and stimulate bone regeneration. The production of such materials in a mesoporous form allowed scientists to dramatically expand the versatility of oxide-based glass systems as well as their applications in biomedicine. These nanostructured materials, called mesoporous bioactive glasses (MBGs), not only exhibit an ultrafast mineralization rate but can be used as vehicles for the sustained delivery of drugs, which are hosted inside the mesopores, and therapeutic ions, which are released during material dissolution in contact with biological fluids. This review paper summarizes the main strategies for the preparation of MBGs, as well as their properties and applications in the biomedical field, with an emphasis on the methodological aspects and the promise of hierarchical systems with multiscale porosity.
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spelling doaj.art-ba8751d9e2dd434d88899deace4a24862023-11-21T01:56:00ZengMDPI AGNanomaterials2079-49912020-12-011012257110.3390/nano10122571A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and ApplicationsCarla Migneco0Elisa Fiume1Enrica Verné2Francesco Baino3Department of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, ItalyDepartment of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, ItalyDepartment of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, ItalyDepartment of Applied Science and Technology (DISAT), Institute of Materials Physics and Engineering, Politecnico di Torino, 10129 Torino, ItalyBioactive glasses (BGs) are traditionally known to be able to bond to living bone and stimulate bone regeneration. The production of such materials in a mesoporous form allowed scientists to dramatically expand the versatility of oxide-based glass systems as well as their applications in biomedicine. These nanostructured materials, called mesoporous bioactive glasses (MBGs), not only exhibit an ultrafast mineralization rate but can be used as vehicles for the sustained delivery of drugs, which are hosted inside the mesopores, and therapeutic ions, which are released during material dissolution in contact with biological fluids. This review paper summarizes the main strategies for the preparation of MBGs, as well as their properties and applications in the biomedical field, with an emphasis on the methodological aspects and the promise of hierarchical systems with multiscale porosity.https://www.mdpi.com/2079-4991/10/12/2571bioactive glassmesoporoussol–gelscaffoldporositybioactivity
spellingShingle Carla Migneco
Elisa Fiume
Enrica Verné
Francesco Baino
A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications
Nanomaterials
bioactive glass
mesoporous
sol–gel
scaffold
porosity
bioactivity
title A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications
title_full A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications
title_fullStr A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications
title_full_unstemmed A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications
title_short A Guided Walk through the World of Mesoporous Bioactive Glasses (MBGs): Fundamentals, Processing, and Applications
title_sort guided walk through the world of mesoporous bioactive glasses mbgs fundamentals processing and applications
topic bioactive glass
mesoporous
sol–gel
scaffold
porosity
bioactivity
url https://www.mdpi.com/2079-4991/10/12/2571
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