Development and characterization of amphotericin B nanoemulsion-loaded mucoadhesive gel for treatment of vulvovaginal candidiasis

Development and characterization of amphotericin B nanoemulsion-loaded mucoadhesive gel for treatment of vulvovaginal candidiasis

Despite being recognized as the “gold standard” for treating azole-resistant vulvovaginal candidiasis, amphotericin B (AmB), an amphoteric molecule, has not been widely used due to serious issues with solubility and permeability. In light of the aforementioned, the objective of the present study was...

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Bibliographic Details
Main Authors: Mrunal U. Patil, Amarjitsing P. Rajput, Veena S. Belgamwar, Shailesh S. Chalikwar
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Amphotericin B
Nanoemulsion
Aloe vera gel
Vaginal candidiasis
Vaginal lavage test
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022027773

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