A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023

ABSTRACTRubella is a major cause of congenital defects, and the presence of rubella infection in a pregnant woman may lead to fetal death or congenital defects known as congenital rubella syndrome(CRS). Since China has not yet established a national CRS surveillance system, the true incidence cannot...

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Main Authors: Xiaoying Gong, Canjie Zheng, Quanjun Fang, Wenjie Xu, Zhiying Yin
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2334917
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author Xiaoying Gong
Canjie Zheng
Quanjun Fang
Wenjie Xu
Zhiying Yin
author_facet Xiaoying Gong
Canjie Zheng
Quanjun Fang
Wenjie Xu
Zhiying Yin
author_sort Xiaoying Gong
collection DOAJ
description ABSTRACTRubella is a major cause of congenital defects, and the presence of rubella infection in a pregnant woman may lead to fetal death or congenital defects known as congenital rubella syndrome(CRS). Since China has not yet established a national CRS surveillance system, the true incidence cannot be determined. To understand the disease burden and epidemiological characteristics of CRS cases in China, the article reports the first case of CRS in Quzhou, China, and conducts a retrospective analysis of related cases that have been reported in China over the past decade. Because the availability of rubella-containing vaccines (RCV) was not widespread in China before 2008, women of childbearing age born before 2008 are generally unvaccinated against RCV. Due to the lack of routine CRS monitoring and screening, CRS is underreported in China. Vaccination of nonimmune women of childbearing age with RCV and establishing a sensitive and timely case-based CRS surveillance system can accelerate the elimination of rubella and CRS.
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spelling doaj.art-ba8a2837a8f54c0bac2a24ef9c4de5a92024-04-08T02:04:37ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2334917A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023Xiaoying Gong0Canjie Zheng1Quanjun Fang2Wenjie Xu3Zhiying Yin4Department of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, ChinaDepartment of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, ChinaDepartment of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, ChinaDepartment of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, ChinaDepartment of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, ChinaABSTRACTRubella is a major cause of congenital defects, and the presence of rubella infection in a pregnant woman may lead to fetal death or congenital defects known as congenital rubella syndrome(CRS). Since China has not yet established a national CRS surveillance system, the true incidence cannot be determined. To understand the disease burden and epidemiological characteristics of CRS cases in China, the article reports the first case of CRS in Quzhou, China, and conducts a retrospective analysis of related cases that have been reported in China over the past decade. Because the availability of rubella-containing vaccines (RCV) was not widespread in China before 2008, women of childbearing age born before 2008 are generally unvaccinated against RCV. Due to the lack of routine CRS monitoring and screening, CRS is underreported in China. Vaccination of nonimmune women of childbearing age with RCV and establishing a sensitive and timely case-based CRS surveillance system can accelerate the elimination of rubella and CRS.https://www.tandfonline.com/doi/10.1080/21645515.2024.2334917Rubellacongenital rubella syndromerubella-containing vaccinesurveillance systemChina
spellingShingle Xiaoying Gong
Canjie Zheng
Quanjun Fang
Wenjie Xu
Zhiying Yin
A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023
Human Vaccines & Immunotherapeutics
Rubella
congenital rubella syndrome
rubella-containing vaccine
surveillance system
China
title A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023
title_full A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023
title_fullStr A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023
title_full_unstemmed A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023
title_short A case of congenital rubella syndrome and epidemiology of related cases in China, 2014–2023
title_sort case of congenital rubella syndrome and epidemiology of related cases in china 2014 2023
topic Rubella
congenital rubella syndrome
rubella-containing vaccine
surveillance system
China
url https://www.tandfonline.com/doi/10.1080/21645515.2024.2334917
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