In utero transplantation of myoblasts and adipose-derived mesenchymal stem cells to murine models of Duchenne muscular dystrophy does not lead to engraftment and frequently results in fetal death

In utero transplantation of myoblasts and adipose-derived mesenchymal stem cells to murine models of Duchenne muscular dystrophy does not lead to engraftment and frequently results in fetal death

Introduction: Duchenne muscular dystrophy (DMD) is a progressive disease that leads to damage of muscle and myocardium due to genetic abnormalities in the dystrophin gene. In utero cell transplantation that might facilitate allogenic transplantation is worth considering to treat this disease. Method...

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Bibliographic Details
Main Authors: Yuki Kihara, Yukie Tanaka, Masanari Ikeda, Jun Homma, Ryo Takagi, Keiko Ishigaki, Keitaro Yamanouchi, Hiroaki Honda, Satoru Nagata, Masayuki Yamato
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Regenerative Therapy
Subjects:
Fetal therapy
In utero transplantation
Myoblasts
Adipose-derived mesenchymal stem cells
Duchenne muscular dystrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320422001006

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