The advances in immunotherapy biomarkers of small cell lung cancer
There is no obvious breakthrough in treatment for small cell lung cancer (SCLC) in more than 30 years, and the prognosis has not improved significantly. With the opening of the immune era, immune checkpoint inhibitors have made breakthroughs in SCLC treatment, but the overall benefit popul...
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| Format: | Article |
| Language: | English |
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Editorial Office of China Oncology
2021-07-01
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| Series: | Zhongguo aizheng zazhi |
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| Online Access: | http://www.china-oncology.com/fileup/1007-3639/PDF/20210710.pdf |
| _version_ | 1811198075443609600 |
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| author | XIE Mengqing, CHU Xiangling, ZHOU Juan, SU Chunxia |
| author_facet | XIE Mengqing, CHU Xiangling, ZHOU Juan, SU Chunxia |
| author_sort | XIE Mengqing, CHU Xiangling, ZHOU Juan, SU Chunxia |
| collection | DOAJ |
| description | There is no obvious breakthrough in treatment for small cell lung cancer (SCLC) in more than 30 years, and the prognosis has not improved significantly. With the opening of the immune era, immune checkpoint inhibitors have made breakthroughs in SCLC treatment, but the overall benefit population is limited. How to select patients accurately and how to increase the efficacy of immunotherapy are hot topics in SCLC research. Therefore, this article summarized the current status of SCLC with focus on biomarkers related to SCLC immunotherapy, reviewed the progress in the research of immunotherapy markers in recent years, to provide clues and ideas for future immunotherapeutic strategies. |
| first_indexed | 2024-04-12T01:24:31Z |
| format | Article |
| id | doaj.art-ba8f00ccc3f4464aae38e6a3b84ad082 |
| institution | Directory Open Access Journal |
| issn | 1007-3639 |
| language | English |
| last_indexed | 2024-04-12T01:24:31Z |
| publishDate | 2021-07-01 |
| publisher | Editorial Office of China Oncology |
| record_format | Article |
| series | Zhongguo aizheng zazhi |
| spelling | doaj.art-ba8f00ccc3f4464aae38e6a3b84ad0822022-12-22T03:53:42ZengEditorial Office of China OncologyZhongguo aizheng zazhi1007-36392021-07-0131763563910.19401/j.cnki.1007-3639.2021.07.010The advances in immunotherapy biomarkers of small cell lung cancerXIE Mengqing, CHU Xiangling, ZHOU Juan, SU Chunxia0Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China There is no obvious breakthrough in treatment for small cell lung cancer (SCLC) in more than 30 years, and the prognosis has not improved significantly. With the opening of the immune era, immune checkpoint inhibitors have made breakthroughs in SCLC treatment, but the overall benefit population is limited. How to select patients accurately and how to increase the efficacy of immunotherapy are hot topics in SCLC research. Therefore, this article summarized the current status of SCLC with focus on biomarkers related to SCLC immunotherapy, reviewed the progress in the research of immunotherapy markers in recent years, to provide clues and ideas for future immunotherapeutic strategies.http://www.china-oncology.com/fileup/1007-3639/PDF/20210710.pdfsmall cell lung cancer| immunotherapy|biomarkers |
| spellingShingle | XIE Mengqing, CHU Xiangling, ZHOU Juan, SU Chunxia The advances in immunotherapy biomarkers of small cell lung cancer Zhongguo aizheng zazhi small cell lung cancer| immunotherapy|biomarkers |
| title | The advances in immunotherapy biomarkers of small cell lung cancer |
| title_full | The advances in immunotherapy biomarkers of small cell lung cancer |
| title_fullStr | The advances in immunotherapy biomarkers of small cell lung cancer |
| title_full_unstemmed | The advances in immunotherapy biomarkers of small cell lung cancer |
| title_short | The advances in immunotherapy biomarkers of small cell lung cancer |
| title_sort | advances in immunotherapy biomarkers of small cell lung cancer |
| topic | small cell lung cancer| immunotherapy|biomarkers |
| url | http://www.china-oncology.com/fileup/1007-3639/PDF/20210710.pdf |
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