Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol)
Obesity is a serious metabolic disease that significantly increases cardiovascular risks and other health complications. Sarcopenia is an independent risk factor for morbidity and mortality in patients suffering from obesity that increases the health risks and is associated with cardiac, respirator...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2023-03-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/7786 |
| _version_ | 1797261389181485056 |
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| author | Marek Bužga Matej Pekar Jaroslav Uchytil Veronika Horká Jan Malůš Dominik Vilímek Zdeněk Švagera Petr Kutáč Pavol Holéczy |
| author_facet | Marek Bužga Matej Pekar Jaroslav Uchytil Veronika Horká Jan Malůš Dominik Vilímek Zdeněk Švagera Petr Kutáč Pavol Holéczy |
| author_sort | Marek Bužga |
| collection | DOAJ |
| description |
Obesity is a serious metabolic disease that significantly increases cardiovascular risks and other health complications. Sarcopenia is an independent risk factor for morbidity and mortality in patients suffering from obesity that increases the health risks and is associated with cardiac, respiratory and other diseases. Bariatric and metabolic surgery (BMS) leads to significant changes in body composition. Our pilot study showed that bariatric patients are at risk of sarcopenia after BMS. This finding resulted in a hypothesis that an exercise plan in the experimental group will lead to postural stabilization and a lower decline in muscle homotopy, further leading to a greater reduction in fat mass and a positive effect of exercise on skeletal muscle volume and strength and endocrine-metabolic function. The aim of the present study is to determine the effect of programmed aerobic and strength training on muscle function, volume, and morphology in patients after BMS. The study is a single-center, randomized clinical trial after sleeve gastrectomy focused on muscle tissue. The experimental group will perform targeted physical activity once a week for 12 months and the training plan will include anaerobic and aerobic components. Magnetic resonance imaging of skeletal muscles will be correlated with the values of densitometry examination and changes in body composition, certain blood parameters of myokines, biomechanical analysis of movement abnormalities, and behavioral and dietary counseling. This study will address the research questions about the effect of programmed training on muscle tissue and muscular functions after BMS.
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| first_indexed | 2024-04-24T23:40:26Z |
| format | Article |
| id | doaj.art-ba90911e0ab24bf68967c0e9eadc264f |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:40:26Z |
| publishDate | 2023-03-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-ba90911e0ab24bf68967c0e9eadc264f2024-03-15T13:22:46ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2023-03-0123210.17305/bjbms.2022.7786Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol)Marek Bužga0https://orcid.org/0000-0002-9554-737XMatej Pekar1https://orcid.org/0000-0001-6238-2276Jaroslav Uchytil2Veronika Horká3https://orcid.org/0000-0003-1923-5742Jan Malůš4https://orcid.org/0000-0001-8984-3378Dominik Vilímek5Zdeněk Švagera6https://orcid.org/0000-0002-7937-3197Petr Kutáč7https://orcid.org/0000-0002-1973-1503Pavol Holéczy8Department of Physiology and Pathophysiology, Medical Faculty, University of Ostrava, Ostrava, Czech Republic Department of Physiology, Medical Faculty, Masaryk University, Brno, Czech Republic; Vascular and miniinvasive surgery center, Hospital AGEL Trinec-Podlesi, Trinec, Czech RepublicHuman Movement Diagnostic Center, University of Ostrava, Ostrava, Czech RepublicHuman Movement Diagnostic Center, University of Ostrava, Ostrava, Czech RepublicHuman Movement Diagnostic Center, University of Ostrava, Ostrava, Czech RepublicDepartment of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, VSB - Technical University of Ostrava, Ostrava, Czech RepublicInstitute of Laboratory Medicine, Medical Faculty, University of Ostrava, Ostrava, Czech RepublicHuman Movement Diagnostic Center, University of Ostrava, Ostrava, Czech RepublicDepartment of surgery, Center of Bariatric Medicine, Hospital AGEL - Ostrava - Vitkovice, Ostrava, Czech Republic; Department of surgical disciplines, Medical Faculty, University of Ostrava, Ostrava, Czech Republic Obesity is a serious metabolic disease that significantly increases cardiovascular risks and other health complications. Sarcopenia is an independent risk factor for morbidity and mortality in patients suffering from obesity that increases the health risks and is associated with cardiac, respiratory and other diseases. Bariatric and metabolic surgery (BMS) leads to significant changes in body composition. Our pilot study showed that bariatric patients are at risk of sarcopenia after BMS. This finding resulted in a hypothesis that an exercise plan in the experimental group will lead to postural stabilization and a lower decline in muscle homotopy, further leading to a greater reduction in fat mass and a positive effect of exercise on skeletal muscle volume and strength and endocrine-metabolic function. The aim of the present study is to determine the effect of programmed aerobic and strength training on muscle function, volume, and morphology in patients after BMS. The study is a single-center, randomized clinical trial after sleeve gastrectomy focused on muscle tissue. The experimental group will perform targeted physical activity once a week for 12 months and the training plan will include anaerobic and aerobic components. Magnetic resonance imaging of skeletal muscles will be correlated with the values of densitometry examination and changes in body composition, certain blood parameters of myokines, biomechanical analysis of movement abnormalities, and behavioral and dietary counseling. This study will address the research questions about the effect of programmed training on muscle tissue and muscular functions after BMS. https://www.bjbms.org/ojs/index.php/bjbms/article/view/7786Sarcopeniaexercisebariatricmetabolicsurgery |
| spellingShingle | Marek Bužga Matej Pekar Jaroslav Uchytil Veronika Horká Jan Malůš Dominik Vilímek Zdeněk Švagera Petr Kutáč Pavol Holéczy Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol) Biomolecules & Biomedicine Sarcopenia exercise bariatric metabolic surgery |
| title | Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol) |
| title_full | Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol) |
| title_fullStr | Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol) |
| title_full_unstemmed | Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol) |
| title_short | Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: The effect of programmed training on the muscle tissue and anthropometric functions – A randomized controlled trial (SarxOb study protocol) |
| title_sort | prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery the effect of programmed training on the muscle tissue and anthropometric functions a randomized controlled trial sarxob study protocol |
| topic | Sarcopenia exercise bariatric metabolic surgery |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/7786 |
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