Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity
The onset of chemotherapy-induced peripheral neurotoxicity (CIPN) is a leading cause of the dose reduction or discontinuation of cancer treatment due to sensory symptoms. Paclitaxel (PTX) can cause painful peripheral neuropathy, with a negative impact on cancer survivors’ quality of life. While rece...
Main Authors: | Cristina Meregalli, Laura Monza, Alessia Chiorazzi, Carla Scali, Chiara Guarnieri, Giulia Fumagalli, Paola Alberti, Eleonora Pozzi, Annalisa Canta, Elisa Ballarini, Virginia Rodriguez-Menendez, Norberto Oggioni, Guido Cavaletti, Paola Marmiroli |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/3/1058 |
Similar Items
-
Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity
by: Annalisa Canta, et al.
Published: (2020-07-01) -
A mechanistic understanding of the relationship between skin innervation and chemotherapy-induced neuropathic pain
by: Cristina Meregalli, et al.
Published: (2022-12-01) -
Paclitaxel, but Not Cisplatin, Affects Satellite Glial Cells in Dorsal Root Ganglia of Rats with Chemotherapy-Induced Peripheral Neurotoxicity
by: Eleonora Pozzi, et al.
Published: (2023-01-01) -
Keratinocyte Biomarkers Distinguish Painful Diabetic Peripheral Neuropathy Patients and Correlate With Topical Lidocaine Responsiveness
by: Phillip J. Albrecht, et al.
Published: (2021-12-01) -
DHP107, a novel oral paclitaxel formulation induces less peripheral neuropathic pain and pain-related molecular alteration than intravenous paclitaxel preparation in rat
by: Md. Mahbubur Rahman, et al.
Published: (2019-08-01)