Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections
Abstract Background Complications from osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) include oro-cutaneous fistulas, necrotic bone exposure, soft-tissue defects, and pathologic fractures. The fibula free flap (FFF) is a common free flap method used to reconstruct t...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-12-01
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| Series: | Maxillofacial Plastic and Reconstructive Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40902-022-00366-2 |
| _version_ | 1811203726170390528 |
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| author | Hyemin Oh Dohyun Kwon Jaemyung Ahn Jun-Young Paeng |
| author_facet | Hyemin Oh Dohyun Kwon Jaemyung Ahn Jun-Young Paeng |
| author_sort | Hyemin Oh |
| collection | DOAJ |
| description | Abstract Background Complications from osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) include oro-cutaneous fistulas, necrotic bone exposure, soft-tissue defects, and pathologic fractures. The fibula free flap (FFF) is a common free flap method used to reconstruct the mandible in severe cases. Recently, we have used the FFF successfully for the reconstruction of ORN and MRONJ mandibular defects. We report this method as a recommended technique for the treatment of ORN and MRONJ and the management method of postoperative infections. Methods Four patients who were diagnosed with ORN of the mandible and 3 patients who were diagnosed with MRONJ of the mandible were included in the study. Among the 7 patients, 3 patients also had pathologic fractures. Partial mandibulectomy and FFF reconstruction were performed at the Department of Oral and Maxillofacial Surgery, Samsung Medical Center from April 2019 to March 2021. Results All 7 patients recovered following the reconstruction of the defect by FFF. Four patients experienced infections after surgery and pus cultures were performed. All were well healed without flap damage after changing the antibiotics by consultation with infectious medicine experts. Conclusion FFF is a widely used method and can provide an extensive flap to reconstruct the mandible, especially those affected by ORN or MRONJ. If an infection occurs after surgery, appropriate antibiotic changes should be made through cooperation with the infectious medicine department. Therefore, FFF is a well-established and recommended method even in cases of challenging reconstruction. |
| first_indexed | 2024-04-12T02:59:48Z |
| format | Article |
| id | doaj.art-ba93c059d6f74fce989cfe4cb50dbb97 |
| institution | Directory Open Access Journal |
| issn | 2288-8586 |
| language | English |
| last_indexed | 2024-04-12T02:59:48Z |
| publishDate | 2022-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Maxillofacial Plastic and Reconstructive Surgery |
| spelling | doaj.art-ba93c059d6f74fce989cfe4cb50dbb972022-12-22T03:50:41ZengSpringerOpenMaxillofacial Plastic and Reconstructive Surgery2288-85862022-12-014411810.1186/s40902-022-00366-2Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infectionsHyemin Oh0Dohyun Kwon1Jaemyung Ahn2Jun-Young Paeng3Department of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of MedicineAbstract Background Complications from osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ) include oro-cutaneous fistulas, necrotic bone exposure, soft-tissue defects, and pathologic fractures. The fibula free flap (FFF) is a common free flap method used to reconstruct the mandible in severe cases. Recently, we have used the FFF successfully for the reconstruction of ORN and MRONJ mandibular defects. We report this method as a recommended technique for the treatment of ORN and MRONJ and the management method of postoperative infections. Methods Four patients who were diagnosed with ORN of the mandible and 3 patients who were diagnosed with MRONJ of the mandible were included in the study. Among the 7 patients, 3 patients also had pathologic fractures. Partial mandibulectomy and FFF reconstruction were performed at the Department of Oral and Maxillofacial Surgery, Samsung Medical Center from April 2019 to March 2021. Results All 7 patients recovered following the reconstruction of the defect by FFF. Four patients experienced infections after surgery and pus cultures were performed. All were well healed without flap damage after changing the antibiotics by consultation with infectious medicine experts. Conclusion FFF is a widely used method and can provide an extensive flap to reconstruct the mandible, especially those affected by ORN or MRONJ. If an infection occurs after surgery, appropriate antibiotic changes should be made through cooperation with the infectious medicine department. Therefore, FFF is a well-established and recommended method even in cases of challenging reconstruction.https://doi.org/10.1186/s40902-022-00366-2Osteoradionecrosis (ORN)Medication-related osteonecrosis of the jaws (MRONJ)MandibleFibula free flapInfection |
| spellingShingle | Hyemin Oh Dohyun Kwon Jaemyung Ahn Jun-Young Paeng Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections Maxillofacial Plastic and Reconstructive Surgery Osteoradionecrosis (ORN) Medication-related osteonecrosis of the jaws (MRONJ) Mandible Fibula free flap Infection |
| title | Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections |
| title_full | Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections |
| title_fullStr | Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections |
| title_full_unstemmed | Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections |
| title_short | Reconstruction of mandibular defects in osteoradionecrosis and medication-related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections |
| title_sort | reconstruction of mandibular defects in osteoradionecrosis and medication related osteonecrosis of the jaw using fibula free flap and management of postoperative wound infections |
| topic | Osteoradionecrosis (ORN) Medication-related osteonecrosis of the jaws (MRONJ) Mandible Fibula free flap Infection |
| url | https://doi.org/10.1186/s40902-022-00366-2 |
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