Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method
<p>Abstract</p> <p>Polyurethane nanofibers containing calcium chloride (CaCl<sub>2</sub>) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl<sub>2</sub> were electrospu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2011-01-01
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| Series: | Nanoscale Research Letters |
| Subjects: | |
| Online Access: | http://www.nanoscalereslett.com/content/6/1/2 |
| Summary: | <p>Abstract</p> <p>Polyurethane nanofibers containing calcium chloride (CaCl<sub>2</sub>) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl<sub>2</sub> were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl<sub>2</sub> composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl<sub>2</sub> salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl<sub>2</sub> composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl<sub>2</sub> composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.</p> |
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| ISSN: | 1931-7573 1556-276X |