Cell membrane-bound toll-like receptor-1/2/4/6 monomers and -2 heterodimer inhibit enterovirus 71 replication by activating the antiviral innate response
Host immune activation is critical for enterovirus 71 (EV71) clearance and immunopathogenesis. However, the mechanism of innate immune activation, especially of cell membrane-bound toll-like receptors (TLRs), against EV71 remains unknown. We previously demonstrated that TLR2 and its heterodimer inhi...
Main Authors: | Ping-Ping Sun, Dan Li, Meng Su, Qing Ren, Wen-Ping Guo, Jiang-Li Wang, Luan-Ying Du, Guang-Cheng Xie |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1187035/full |
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