Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies

Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies

Rho family guanosine triphosphatases (GTPases) regulate cellular signaling and cytoskeletal dynamics, playing a pivotal role in cell adhesion, migration, and cell cycle progression. The Rac subfamily of Rho GTPases consists of three highly homologous proteins, Rac 1–3. The proper function of Rac1 an...

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Bibliographic Details
Main Authors:	Marcello Scala, Masashi Nishikawa, Koh-ichi Nagata, Pasquale Striano
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Cells
Subjects:	Rho family guanosine triphosphatases RAC1 RAC3 cytoskeletal dynamics neuronal development neurodevelopmental disorder
Online Access:	https://www.mdpi.com/2073-4409/10/12/3395

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