LINE-1 ORF1p does not determine substrate preference for human/orangutan SVA and gibbon LAVA

Abstract Background Non-autonomous VNTR (Variable Number of Tandem Repeats) composite retrotransposons – SVA (SINE-R-VNTR-Alu) and LAVA (L1-Alu-VNTR-Alu) – are specific to hominoid primates. SVA expanded in great apes, LAVA in gibbon. Both SVA and LAVA have been shown to be mobilized by the autonomo...

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Bibliographic Details
Main Author: Annette Damert
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Mobile DNA
Online Access:http://link.springer.com/article/10.1186/s13100-020-00222-y