Protective effects of Qing-Re-Huo-Xue formula on bleomycin-induced pulmonary fibrosis through the p53/IGFBP3 pathway

Protective effects of Qing-Re-Huo-Xue formula on bleomycin-induced pulmonary fibrosis through the p53/IGFBP3 pathway

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing lung disease with high mortality. Inflammation and epithelial mesenchymal transformation (EMT) may play an important role in the occurrence and development of IPF. Qing-Re-Huo-Xue formula (QRHXF) has been use...

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Bibliographic Details
Main Authors: Fangyong Yang, Wenjing Du, Zhao Tang, Ying Wei, Jingcheng Dong
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Chinese Medicine
Subjects:
Qing-Re-Huo-Xue formula
Pulmonary fibrosis
Inflammation
EMT
TMT proteomics
p53/IGFBP3 pathway
Online Access:https://doi.org/10.1186/s13020-023-00730-y

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