Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys
Abstract Calcium-based alloys can be promising candidates for use as biodegradable implants because of attractive properties as mechanical, corrosive, and biocompatible. In the work, the biocompatibility authors discussed the results of the Ca32Mg12Zn38Yb18−xBx (x = 0, 1, 2, 3 at.%) and Ca32Mg12Zn38...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-12-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-25069-6 |
| _version_ | 1811188232236302336 |
|---|---|
| author | Dawid Szyba Robert Kubina Katarzyna Młynarek-Żak Adrian Radoń Aneta Kania Rafał Babilas |
| author_facet | Dawid Szyba Robert Kubina Katarzyna Młynarek-Żak Adrian Radoń Aneta Kania Rafał Babilas |
| author_sort | Dawid Szyba |
| collection | DOAJ |
| description | Abstract Calcium-based alloys can be promising candidates for use as biodegradable implants because of attractive properties as mechanical, corrosive, and biocompatible. In the work, the biocompatibility authors discussed the results of the Ca32Mg12Zn38Yb18−xBx (x = 0, 1, 2, 3 at.%) and Ca32Mg12Zn38Yb18−2xBxAux (x = 1, 2 at.%) alloys. The tests were performed using a MTT assay. The corrosion behavior of such Ca-based alloys in PWE fluid at 37 °C was studied and compared with the results in Ringer’s solution from previous works. Electrochemical tests were presented by open circuit potential and potentiodynamic curves. Different concentrations of boron and gold in the alloys caused changes in the corrosion results. The best corrosion resistance in PWE solution was observed for the Ca-based alloy with 2 at.% Au due to the lowest value of the corrosion current density (j corr), equal to 10.6 µA·cm−2. A slightly higher value of j corr was obtained for the Ca32Mg12Zn38Yb15B3 alloy with the lowest roughness values. The results of the cytotoxicity tests also showed that the alloy with 3 at.% boron was characterized by the highest cell viability. The investigation results discussed in the work allow us to suggest that the presented calcium alloys with 3 at.% of B, and 2 at.% of Au addition may be promising materials for the use in implantology. |
| first_indexed | 2024-04-11T14:16:48Z |
| format | Article |
| id | doaj.art-baaa998d04a74f248824e41f2f73d1c1 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T14:16:48Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-baaa998d04a74f248824e41f2f73d1c12022-12-22T04:19:24ZengNature PortfolioScientific Reports2045-23222022-12-0112111310.1038/s41598-022-25069-6Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloysDawid Szyba0Robert Kubina1Katarzyna Młynarek-Żak2Adrian Radoń3Aneta Kania4Rafał Babilas5Department of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of TechnologyDepartment of Pathology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in KatowiceDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of TechnologyDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of TechnologyDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of TechnologyDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of TechnologyAbstract Calcium-based alloys can be promising candidates for use as biodegradable implants because of attractive properties as mechanical, corrosive, and biocompatible. In the work, the biocompatibility authors discussed the results of the Ca32Mg12Zn38Yb18−xBx (x = 0, 1, 2, 3 at.%) and Ca32Mg12Zn38Yb18−2xBxAux (x = 1, 2 at.%) alloys. The tests were performed using a MTT assay. The corrosion behavior of such Ca-based alloys in PWE fluid at 37 °C was studied and compared with the results in Ringer’s solution from previous works. Electrochemical tests were presented by open circuit potential and potentiodynamic curves. Different concentrations of boron and gold in the alloys caused changes in the corrosion results. The best corrosion resistance in PWE solution was observed for the Ca-based alloy with 2 at.% Au due to the lowest value of the corrosion current density (j corr), equal to 10.6 µA·cm−2. A slightly higher value of j corr was obtained for the Ca32Mg12Zn38Yb15B3 alloy with the lowest roughness values. The results of the cytotoxicity tests also showed that the alloy with 3 at.% boron was characterized by the highest cell viability. The investigation results discussed in the work allow us to suggest that the presented calcium alloys with 3 at.% of B, and 2 at.% of Au addition may be promising materials for the use in implantology.https://doi.org/10.1038/s41598-022-25069-6 |
| spellingShingle | Dawid Szyba Robert Kubina Katarzyna Młynarek-Żak Adrian Radoń Aneta Kania Rafał Babilas Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys Scientific Reports |
| title | Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys |
| title_full | Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys |
| title_fullStr | Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys |
| title_full_unstemmed | Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys |
| title_short | Evaluation of the biocompability and corrosion activity of resorbable CaMgZnYbBAu alloys |
| title_sort | evaluation of the biocompability and corrosion activity of resorbable camgznybbau alloys |
| url | https://doi.org/10.1038/s41598-022-25069-6 |
| work_keys_str_mv | AT dawidszyba evaluationofthebiocompabilityandcorrosionactivityofresorbablecamgznybbaualloys AT robertkubina evaluationofthebiocompabilityandcorrosionactivityofresorbablecamgznybbaualloys AT katarzynamłynarekzak evaluationofthebiocompabilityandcorrosionactivityofresorbablecamgznybbaualloys AT adrianradon evaluationofthebiocompabilityandcorrosionactivityofresorbablecamgznybbaualloys AT anetakania evaluationofthebiocompabilityandcorrosionactivityofresorbablecamgznybbaualloys AT rafałbabilas evaluationofthebiocompabilityandcorrosionactivityofresorbablecamgznybbaualloys |