Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health
Introduction: Deficiency of CoQ 10 was found in human inflamed gingiva and has been found to be responsible for periodontal destruction. Aim: To evaluate the effectiveness of CoQ 10 supplementation as an adjunct to scaling and rootplaning in reducing gingival inflammation and periodontal pocket...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-08-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6291/13486_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1819144095150374912 |
|---|---|
| author | Sathish Manthena Mulpuri. Venkata. Ramoji Rao Lakshmi Preethi Penubolu Madhusudhan Putcha Anumolu Venkata Naga Sri Harsha |
| author_facet | Sathish Manthena Mulpuri. Venkata. Ramoji Rao Lakshmi Preethi Penubolu Madhusudhan Putcha Anumolu Venkata Naga Sri Harsha |
| author_sort | Sathish Manthena |
| collection | DOAJ |
| description | Introduction: Deficiency of CoQ 10 was found in human inflamed
gingiva and has been found to be responsible for periodontal
destruction.
Aim: To evaluate the effectiveness of CoQ 10 supplementation
as an adjunct to scaling and rootplaning in reducing gingival
inflammation and periodontal pocket depth.
Materials and Methods: The study was a randomized, doubleblind, controlled, parallel group design clinical trial. Thirty subjects
with plaque induced gingival inflammation and having atleast
three nonadjacent interproximal sites with a probing pocket depth
≥ 5mm were included in the study. The subjects were randomly
divided into two groups. The test group (n=15) in which patients
were given oral CoQ10 supplements after scaling and root planing
and the control group (n=15) in which patients were given an oral
placebo after scaling and rootplaning. The plaque index, gingival
index and probing depth were recorded at baseline, 1 month and
3 months. Statistical analysis done by using Student’s paired t-test
for intragroup comparison and unpaired t-test for inter-group
comparison.
Results: Both the groups showed marked reduction of afore
mentioned periodontal parameters at one month and three months
when compared to baseline. Though there was no significant
difference in plaque index and probing pocket depth between the
two groups at any given time period, test group showed significant
difference in gingival inflammation at one month and three months
when compared to control group.
Conclusion: In the present study use of Coenzyme Q10 oral
supplements as an adjunct to scaling and root planing showed
significant reduction in gingival inflammation when compared to
scaling and rootplaning alone. |
| first_indexed | 2024-12-22T12:36:41Z |
| format | Article |
| id | doaj.art-baaf891ef54248f0969650533a400960 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T12:36:41Z |
| publishDate | 2015-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-baaf891ef54248f0969650533a4009602022-12-21T18:25:33ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-08-0198ZC26ZC2810.7860/JCDR/2015/13486.6291Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal HealthSathish Manthena0Mulpuri. Venkata. Ramoji Rao1Lakshmi Preethi Penubolu2Madhusudhan Putcha3Anumolu Venkata Naga Sri Harsha4Reader, Department of Periodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnoutpalli, India.Professor and Head, Department of Periodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnoutpalli, India.Reader, Department of Periodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnoutpalli, India.Senior Lecturer, Department of Periodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnoutpalli, India.Senior Lecturer, Department of Periodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnoutpalli, India.Introduction: Deficiency of CoQ 10 was found in human inflamed gingiva and has been found to be responsible for periodontal destruction. Aim: To evaluate the effectiveness of CoQ 10 supplementation as an adjunct to scaling and rootplaning in reducing gingival inflammation and periodontal pocket depth. Materials and Methods: The study was a randomized, doubleblind, controlled, parallel group design clinical trial. Thirty subjects with plaque induced gingival inflammation and having atleast three nonadjacent interproximal sites with a probing pocket depth ≥ 5mm were included in the study. The subjects were randomly divided into two groups. The test group (n=15) in which patients were given oral CoQ10 supplements after scaling and root planing and the control group (n=15) in which patients were given an oral placebo after scaling and rootplaning. The plaque index, gingival index and probing depth were recorded at baseline, 1 month and 3 months. Statistical analysis done by using Student’s paired t-test for intragroup comparison and unpaired t-test for inter-group comparison. Results: Both the groups showed marked reduction of afore mentioned periodontal parameters at one month and three months when compared to baseline. Though there was no significant difference in plaque index and probing pocket depth between the two groups at any given time period, test group showed significant difference in gingival inflammation at one month and three months when compared to control group. Conclusion: In the present study use of Coenzyme Q10 oral supplements as an adjunct to scaling and root planing showed significant reduction in gingival inflammation when compared to scaling and rootplaning alone.https://jcdr.net/articles/PDF/6291/13486_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdfantioxidantsgingival inflammationperiodontitis |
| spellingShingle | Sathish Manthena Mulpuri. Venkata. Ramoji Rao Lakshmi Preethi Penubolu Madhusudhan Putcha Anumolu Venkata Naga Sri Harsha Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health Journal of Clinical and Diagnostic Research antioxidants gingival inflammation periodontitis |
| title | Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health |
| title_full | Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health |
| title_fullStr | Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health |
| title_full_unstemmed | Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health |
| title_short | Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health |
| title_sort | effectiveness of coq10 oral supplements as an adjunct to scaling and root planing in improving periodontal health |
| topic | antioxidants gingival inflammation periodontitis |
| url | https://jcdr.net/articles/PDF/6291/13486_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
| work_keys_str_mv | AT sathishmanthena effectivenessofcoq10oralsupplementsasanadjuncttoscalingandrootplaninginimprovingperiodontalhealth AT mulpurivenkataramojirao effectivenessofcoq10oralsupplementsasanadjuncttoscalingandrootplaninginimprovingperiodontalhealth AT lakshmipreethipenubolu effectivenessofcoq10oralsupplementsasanadjuncttoscalingandrootplaninginimprovingperiodontalhealth AT madhusudhanputcha effectivenessofcoq10oralsupplementsasanadjuncttoscalingandrootplaninginimprovingperiodontalhealth AT anumoluvenkatanagasriharsha effectivenessofcoq10oralsupplementsasanadjuncttoscalingandrootplaninginimprovingperiodontalhealth |