Soft Poly(N-vinylcaprolactam) Based Aqueous Particles
Soft nanoparticles are an important class of material with potential to be used as carriers of active compounds. Swollen, penetrable particles can act as a host for the active ingredients and provide stability, stimuli-responsiveness and recyclability for the guest. Thermoresponsive colloidal gel pa...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Chemical Society
2022-06-01
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| Series: | Acta Chimica Slovenica |
| Subjects: | |
| Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/7430 |
| _version_ | 1797962891266097152 |
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| author | Joonas Siirilä Heikki Tenhu |
| author_facet | Joonas Siirilä Heikki Tenhu |
| author_sort | Joonas Siirilä |
| collection | DOAJ |
| description | Soft nanoparticles are an important class of material with potential to be used as carriers of active compounds. Swollen, penetrable particles can act as a host for the active ingredients and provide stability, stimuli-responsiveness and recyclability for the guest. Thermoresponsive colloidal gel particles are especially attractive for such applications due to the extremely soft structure, size and responsiveness. Poly(N-vinylcaprolactam) (PNVCL) is a much studied, popular thermoresponsive polymer. The polymer has low toxicity and the phase transition temperature is close to body temperature. During the phase transition, the polymer becomes less soluble, the particle expels a large part of water and the particle collapses to a more compact form. The diffusion of material in and from the particles is largely affected by this transition. As the solubility of the polymer changes, so do the interactions with the loaded compound. This feature article focuses on the synthetic methods, properties and applications of soft PNVCL particles. |
| first_indexed | 2024-04-11T01:20:56Z |
| format | Article |
| id | doaj.art-bab0e93d465647bbba3910e725e16b27 |
| institution | Directory Open Access Journal |
| issn | 1318-0207 1580-3155 |
| language | English |
| last_indexed | 2024-04-11T01:20:56Z |
| publishDate | 2022-06-01 |
| publisher | Slovenian Chemical Society |
| record_format | Article |
| series | Acta Chimica Slovenica |
| spelling | doaj.art-bab0e93d465647bbba3910e725e16b272023-01-03T11:28:42ZengSlovenian Chemical SocietyActa Chimica Slovenica1318-02071580-31552022-06-0169225126010.17344/acsi.2022.74301075Soft Poly(N-vinylcaprolactam) Based Aqueous ParticlesJoonas Siirilä0Heikki Tenhu1University of HelsinkiUniversity of HelsinkiSoft nanoparticles are an important class of material with potential to be used as carriers of active compounds. Swollen, penetrable particles can act as a host for the active ingredients and provide stability, stimuli-responsiveness and recyclability for the guest. Thermoresponsive colloidal gel particles are especially attractive for such applications due to the extremely soft structure, size and responsiveness. Poly(N-vinylcaprolactam) (PNVCL) is a much studied, popular thermoresponsive polymer. The polymer has low toxicity and the phase transition temperature is close to body temperature. During the phase transition, the polymer becomes less soluble, the particle expels a large part of water and the particle collapses to a more compact form. The diffusion of material in and from the particles is largely affected by this transition. As the solubility of the polymer changes, so do the interactions with the loaded compound. This feature article focuses on the synthetic methods, properties and applications of soft PNVCL particles.https://journals.matheo.si/index.php/ACSi/article/view/7430microgelnanogelsynthesisresponsivepoly(n-vinyl caprolactam) |
| spellingShingle | Joonas Siirilä Heikki Tenhu Soft Poly(N-vinylcaprolactam) Based Aqueous Particles Acta Chimica Slovenica microgel nanogel synthesis responsive poly(n-vinyl caprolactam) |
| title | Soft Poly(N-vinylcaprolactam) Based Aqueous Particles |
| title_full | Soft Poly(N-vinylcaprolactam) Based Aqueous Particles |
| title_fullStr | Soft Poly(N-vinylcaprolactam) Based Aqueous Particles |
| title_full_unstemmed | Soft Poly(N-vinylcaprolactam) Based Aqueous Particles |
| title_short | Soft Poly(N-vinylcaprolactam) Based Aqueous Particles |
| title_sort | soft poly n vinylcaprolactam based aqueous particles |
| topic | microgel nanogel synthesis responsive poly(n-vinyl caprolactam) |
| url | https://journals.matheo.si/index.php/ACSi/article/view/7430 |
| work_keys_str_mv | AT joonassiirila softpolynvinylcaprolactambasedaqueousparticles AT heikkitenhu softpolynvinylcaprolactambasedaqueousparticles |