Aging of vestibular function evaluated using correlational vestibular autorotation test
Li-Chun Hsieh,1,2 Hung-Ching Lin,2,3 Guo-She Lee4,5 1Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 2Department of Otolaryngology, Mackay Memorial Hospital, Taipei, Taiwan; 3Department of Audiology and Speech Language Pathology, Mackay Memorial Medica...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2014-09-01
|
| Series: | Clinical Interventions in Aging |
| Subjects: | |
| Online Access: | https://www.dovepress.com/aging-of-vestibular-function-evaluated-using-correlational-vestibular--peer-reviewed-article-CIA |
| _version_ | 1819015801900892160 |
|---|---|
| author | Hsieh LC Lin HC Lee GS |
| author_facet | Hsieh LC Lin HC Lee GS |
| author_sort | Hsieh LC |
| collection | DOAJ |
| description | Li-Chun Hsieh,1,2 Hung-Ching Lin,2,3 Guo-She Lee4,5 1Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 2Department of Otolaryngology, Mackay Memorial Hospital, Taipei, Taiwan; 3Department of Audiology and Speech Language Pathology, Mackay Memorial Medical College, Taipei, Taiwan; 4Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 5Department of Otolaryngology, Taipei City Hospital, Ren-Ai Branch, Taipei, Taiwan Background: Imbalance from degeneration of vestibular end organs is a common problem in the elderly. However, the decline of vestibular function with aging was revealed in few vestibular function tests such as vestibular autorotation test (VAT). In the current VAT, there are drawbacks of poor test–retest reliability, slippage of the sensor at high-speed rotations, and limited data about the effect of aging. We developed a correlational-VAT (cVAT) system that included a small, light sensor (less than 20 g) with wireless data transmission technique to evaluate the aging of vestibular function. Material and methods: We enrolled 53 healthy participants aged between 25 and 75 years and divided them into five age groups. The test conditions were vertical and horizontal head autorotations of frequencies from 0 to 3 Hz with closed eyes or open eyes. The cross-correlation coefficient (CCC) between eye velocity and head velocity was obtained for the head autorotations between 1 Hz and 3 Hz. The mean of the CCCs was used to represent the vestibular function. Results: Age was significantly and negatively correlated with the mean CCC for all test conditions, including horizontal or vertical autorotations with open eyes or closed eyes (P<0.05). The mean CCC with open eyes declined significantly at 55–65 years old and the mean CCC with closed eyes declined significantly at 65–75 years old.Conclusion: Vestibular function evaluated using mean CCC revealed a decline with age, and the function of visual-vestibulo-ocular reflex declined 10 years earlier than the function of vestibulo-ocular reflex. Keywords: vestibular autorotation test, aging, correlation analysis, gyrometry, electro-oculography |
| first_indexed | 2024-12-21T02:37:31Z |
| format | Article |
| id | doaj.art-bab23c1d9dd045e18a4f60b07a567763 |
| institution | Directory Open Access Journal |
| issn | 1178-1998 |
| language | English |
| last_indexed | 2024-12-21T02:37:31Z |
| publishDate | 2014-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Interventions in Aging |
| spelling | doaj.art-bab23c1d9dd045e18a4f60b07a5677632022-12-21T19:18:46ZengDove Medical PressClinical Interventions in Aging1178-19982014-09-01Volume 91463146918204Aging of vestibular function evaluated using correlational vestibular autorotation testHsieh LCLin HCLee GSLi-Chun Hsieh,1,2 Hung-Ching Lin,2,3 Guo-She Lee4,5 1Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 2Department of Otolaryngology, Mackay Memorial Hospital, Taipei, Taiwan; 3Department of Audiology and Speech Language Pathology, Mackay Memorial Medical College, Taipei, Taiwan; 4Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 5Department of Otolaryngology, Taipei City Hospital, Ren-Ai Branch, Taipei, Taiwan Background: Imbalance from degeneration of vestibular end organs is a common problem in the elderly. However, the decline of vestibular function with aging was revealed in few vestibular function tests such as vestibular autorotation test (VAT). In the current VAT, there are drawbacks of poor test–retest reliability, slippage of the sensor at high-speed rotations, and limited data about the effect of aging. We developed a correlational-VAT (cVAT) system that included a small, light sensor (less than 20 g) with wireless data transmission technique to evaluate the aging of vestibular function. Material and methods: We enrolled 53 healthy participants aged between 25 and 75 years and divided them into five age groups. The test conditions were vertical and horizontal head autorotations of frequencies from 0 to 3 Hz with closed eyes or open eyes. The cross-correlation coefficient (CCC) between eye velocity and head velocity was obtained for the head autorotations between 1 Hz and 3 Hz. The mean of the CCCs was used to represent the vestibular function. Results: Age was significantly and negatively correlated with the mean CCC for all test conditions, including horizontal or vertical autorotations with open eyes or closed eyes (P<0.05). The mean CCC with open eyes declined significantly at 55–65 years old and the mean CCC with closed eyes declined significantly at 65–75 years old.Conclusion: Vestibular function evaluated using mean CCC revealed a decline with age, and the function of visual-vestibulo-ocular reflex declined 10 years earlier than the function of vestibulo-ocular reflex. Keywords: vestibular autorotation test, aging, correlation analysis, gyrometry, electro-oculographyhttps://www.dovepress.com/aging-of-vestibular-function-evaluated-using-correlational-vestibular--peer-reviewed-article-CIAvestibular autorotation testagingcorrelation analysisgyrometryelectro-oculography |
| spellingShingle | Hsieh LC Lin HC Lee GS Aging of vestibular function evaluated using correlational vestibular autorotation test Clinical Interventions in Aging vestibular autorotation test aging correlation analysis gyrometry electro-oculography |
| title | Aging of vestibular function evaluated using correlational vestibular autorotation test |
| title_full | Aging of vestibular function evaluated using correlational vestibular autorotation test |
| title_fullStr | Aging of vestibular function evaluated using correlational vestibular autorotation test |
| title_full_unstemmed | Aging of vestibular function evaluated using correlational vestibular autorotation test |
| title_short | Aging of vestibular function evaluated using correlational vestibular autorotation test |
| title_sort | aging of vestibular function evaluated using correlational vestibular autorotation test |
| topic | vestibular autorotation test aging correlation analysis gyrometry electro-oculography |
| url | https://www.dovepress.com/aging-of-vestibular-function-evaluated-using-correlational-vestibular--peer-reviewed-article-CIA |
| work_keys_str_mv | AT hsiehlc agingofvestibularfunctionevaluatedusingcorrelationalvestibularautorotationtest AT linhc agingofvestibularfunctionevaluatedusingcorrelationalvestibularautorotationtest AT leegs agingofvestibularfunctionevaluatedusingcorrelationalvestibularautorotationtest |